Recombinant Mouse SLAMF7/CD319 Protein (His Tag)(Active) (RPES3907)

Recombinant Mouse SLAMF7/CD319 Protein (His Tag)(Active) (RPES3907)
NEU
Artikelnummer Größe Datenblatt Manual SDB Lieferzeit Menge Preis
G-RPES3907.50 50 µg - - -

9 - 20 Werktage*

524,00 €
 
Recombinant Mouse SLAMF7/CD319 Protein (His Tag)(Active) from Assay Genie. Recombinant Mouse... mehr
Produktinformationen "Recombinant Mouse SLAMF7/CD319 Protein (His Tag)(Active) (RPES3907)"
Recombinant Mouse SLAMF7/CD319 Protein (His Tag)(Active) from Assay Genie. Recombinant Mouse SLAMF7/CD319 Protein (His Tag)(Active) is a highly purified recombinant protein produced in HEK293 Cells and for the use in functional assays from Assay Genie.. Protein function: Self-ligand receptor of the signaling lymphocytic activation molecule (SLAM) family. SLAM receptors triggered by homo- or heterotypic cell-cell interactions are modulating the activation and differentiation of a wide variety of immune cells and thus are involved in the regulation and interconnection of both innate and adaptive immune response. Activities are controlled by presence or absence of small cytoplasmic adapter proteins, SH2D1A/SAP and/or SH2D1B/EAT-2 (PubMed:19648922). Mediates natural killer (NK) cell activation through a SH2D1A-independent extracellular signal-regulated ERK-mediated pathway. Positively regulates NK cell functions by a mechanism dependent on the adapter SH2D1B. In addition to heterotypic NK cells-target cells interactions also homotypic interactions between NK cells may contribute to activation. However, in the absence of SH2D1B, inhibits NK cell function. Acts also inhibitory in T-cells (PubMed:19151721). May play a role in lymphocyte adhesion. In LPS-activated monocytes negatively regulates production of proinflammatory cytokines. [The UniProt Consortium]
Schlagworte: CD319, Slamf7, Novel Ly9, SLAM family member 7, Leukocyte cell-surface antigen
Hersteller: Assay Genie
Hersteller-Nr: RPES3907

Eigenschaften

Konjugat: No
Exprimiert in: Human cells
Ursprungsart: Mouse
Format: Highly Purified

Datenbank Information

KEGG ID : K06733 | Passende Produkte
UniProt ID : Q8BHK6 | Passende Produkte

Handhabung & Sicherheit

Lagerung: -20°C
Versand: +4°C (International: +4°C)
Achtung
Nur für Forschungszwecke und Laboruntersuchungen: Nicht für die Anwendung im oder am Menschen!
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