Recombinant Mouse LAMP2/CD107b Protein (His Tag) (RPES4504)

Recombinant Mouse LAMP2/CD107b Protein (His Tag) (RPES4504)
NEU
Artikelnummer Größe Datenblatt Manual SDB Lieferzeit Menge Preis
G-RPES4504.50 50 µg - - -

9 - 20 Werktage*

524,00 €
 
Recombinant Mouse LAMP2/CD107b Protein (His Tag) from Assay Genie. Recombinant Mouse LAMP2/CD107b... mehr
Produktinformationen "Recombinant Mouse LAMP2/CD107b Protein (His Tag) (RPES4504)"
Recombinant Mouse LAMP2/CD107b Protein (His Tag) from Assay Genie. Recombinant Mouse LAMP2/CD107b Protein (His Tag) is a highly purified recombinant protein produced in HEK293 Cells and for the use in functional assays from Assay Genie.. Protein function: Plays an important role in chaperone-mediated autophagy, a process that mediates lysosomal degradation of proteins in response to various stresses and as part of the normal turnover of proteins with a long biological half-live (PubMed:10972293). Functions by binding target proteins, such as GAPDH and MLLT11, and targeting them for lysosomal degradation. Required for the fusion of autophagosomes with lysosomes during autophagy (PubMed:27628032). Cells that lack LAMP2 express normal levels of VAMP8, but fail to accumulate STX17 on autophagosomes, which is the most likely explanation for the lack of fusion between autophagosomes and lysosomes (PubMed:27628032). Required for normal degradation of the contents of autophagosomes (PubMed:10972293, PubMed:12221139). Plays a role in lysosomal protein degradation in response to starvation (PubMed:27628032). Required for efficient MHCII-mediated presentation of exogenous antigens via its function in lysosomal protein degradation, antigenic peptides generated by proteases in the endosomal/lysosomal compartment are captured by nascent MHCII subunits. Is not required for efficient MHCII-mediated presentation of endogenous antigens. [The UniProt Consortium]
Schlagworte: LGP-B, Lamp2, CD107b, Lamp-2, LAMP-2, CD107 antigen-like family member B, Lysosome-associated membrane protein 2, Lysosomal membrane glycoprotein type B, Lysosome-associated membrane glycoprotein 2
Hersteller: Assay Genie
Hersteller-Nr: RPES4504

Eigenschaften

Konjugat: No
Exprimiert in: Human cells
Ursprungsart: Mouse
Format: Highly Purified

Datenbank Information

KEGG ID : K06528 | Passende Produkte
UniProt ID : P17047 | Passende Produkte

Handhabung & Sicherheit

Lagerung: -20°C
Versand: +4°C (International: +4°C)
Achtung
Nur für Forschungszwecke und Laboruntersuchungen: Nicht für die Anwendung im oder am Menschen!
Hier folgen Informationen zur Produktreferenz. mehr
Hier kriegen Sie ein Zertifikat
oder , um Analysenzertifikate anzufordern.
Bewertungen lesen, schreiben und diskutieren... mehr
Kundenbewertungen für "Recombinant Mouse LAMP2/CD107b Protein (His Tag) (RPES4504)"
Bewertung schreiben
oder , um eine Produktbewertung abzugeben.
Zuletzt angesehen