Recombinant Mouse Frizzled-5/FZD5 Protein (Fc Tag) (RPES4588)

Recombinant Mouse Frizzled-5/FZD5 Protein (Fc Tag) (RPES4588)
NEU
Artikelnummer Größe Datenblatt Manual SDB Lieferzeit Menge Preis
G-RPES4588.50 50 µg - - -

9 - 20 Werktage*

524,00 €
 
Recombinant Mouse Frizzled-5/FZD5 Protein (Fc Tag) from Assay Genie. Recombinant Mouse... mehr
Produktinformationen "Recombinant Mouse Frizzled-5/FZD5 Protein (Fc Tag) (RPES4588)"
Recombinant Mouse Frizzled-5/FZD5 Protein (Fc Tag) from Assay Genie. Recombinant Mouse Frizzled-5/FZD5 Protein (Fc Tag) is a highly purified recombinant protein produced in CHO Stable Cells and for the use in functional assays from Assay Genie.. Protein function: Receptor for Wnt proteins (PubMed:11092808, PubMed:18230341). Can activate WNT2, WNT10B, WNT5A, but not WNT2B or WNT4 (in vitro), the in vivo situation may be different since not all of these are known to be coexpressed (PubMed:11092808). In neurons, activation of WNT7A promotes formation of synapses. Functions in the canonical Wnt/beta-catenin signaling pathway (PubMed:18230341). The canonical Wnt/beta-catenin signaling pathway leads to the activation of disheveled proteins, inhibition of GSK-3 kinase, nuclear accumulation of beta-catenin and activation of Wnt target genes (PubMed:18230341). A second signaling pathway involving PKC and calcium fluxes has been seen for some family members, but it is not yet clear if it represents a distinct pathway or if it can be integrated in the canonical pathway, as PKC seems to be required for Wnt-mediated inactivation of GSK-3 kinase. Both pathways seem to involve interactions with G-proteins. May be involved in transduction and intercellular transmission of polarity information during tissue morphogenesis and/or in differentiated tissues (Probable). Plays a role in yolk sac angiogenesis and in placental vascularization (PubMed:11092808). [The UniProt Consortium]
Schlagworte: mFz5, Fzd5, Fz-5, Frizzled-5
Hersteller: Assay Genie
Hersteller-Nr: RPES4588

Eigenschaften

Konjugat: No
Ursprungsart: Mouse
Format: Highly Purified

Datenbank Information

KEGG ID : K02375 | Passende Produkte
UniProt ID : Q9EQD0 | Passende Produkte

Handhabung & Sicherheit

Lagerung: -20°C
Versand: +4°C (International: +4°C)
Achtung
Nur für Forschungszwecke und Laboruntersuchungen: Nicht für die Anwendung im oder am Menschen!
Hier folgen Informationen zur Produktreferenz. mehr
Hier kriegen Sie ein Zertifikat
oder , um Analysenzertifikate anzufordern.
Bewertungen lesen, schreiben und diskutieren... mehr
Kundenbewertungen für "Recombinant Mouse Frizzled-5/FZD5 Protein (Fc Tag) (RPES4588)"
Bewertung schreiben
oder , um eine Produktbewertung abzugeben.
Zuletzt angesehen