Recombinant Human Tumor Necrosis Factor Receptor II/TNFRSF1B/CD120b (Lys288-Ser461, C-6His)

Recombinant Human Tumor Necrosis Factor Receptor II/TNFRSF1B/CD120b (Lys288-Ser461, C-6His)
Artikelnummer Größe Datenblatt Manual SDB Lieferzeit Menge Preis
ABE-32-7637-10 10 µg - -

3 - 11 Werktage*

478,00 €
ABE-32-7637-50 50 µg - -

3 - 11 Werktage*

791,00 €
 
Source: Human Cells. MW :19kD. Recombinant Human Tumor Necrosis Factor Receptor II is produced by... mehr
Produktinformationen "Recombinant Human Tumor Necrosis Factor Receptor II/TNFRSF1B/CD120b (Lys288-Ser461, C-6His)"
Source: Human Cells. MW :19kD. Recombinant Human Tumor Necrosis Factor Receptor II is produced by our Mammalian expression system and the target gene encoding Lys288-Ser461 is expressed with a 6His tag at the C-terminus. Tumor necrosis factor receptor superfamily member 1B(TNFRSF1B) is expressed by the gene TNFRSF1B. The soluble form is produced from the membrane form by proteolytic processing. It can bind to TRAF2, and interacts with BMX. It can act as the receptor with high affinity for TNFSF2/TNF-alpha and approximately 5-fold lower affinity for homotrimeric TNFSF1/lymphotoxin-alpha. The TRAF1/TRAF2 complex recruits the apoptotic suppressors BIRC2 and BIRC3 to TNFRSF1B/TNFR2. This receptor mediates most of the metabolic effects of TNF-alpha. Protein function: Receptor with high affinity for TNFSF2/TNF-alpha and approximately 5-fold lower affinity for homotrimeric TNFSF1/lymphotoxin-alpha. The TRAF1/TRAF2 complex recruits the apoptotic suppressors BIRC2 and BIRC3 to TNFRSF1B/TNFR2. This receptor mediates most of the metabolic effects of TNF-alpha. Isoform 2 blocks TNF-alpha-induced apoptosis, which suggests that it regulates TNF-alpha function by antagonizing its biological activity. [The UniProt Consortium]
Hersteller: Abeomics
Hersteller-Nr: 32-7637

Eigenschaften

Konjugat: No

Handhabung & Sicherheit

Lagerung: +20°C
Versand: +20°C (International: +20°C)
Achtung
Nur für Forschungszwecke und Laboruntersuchungen: Nicht für die Anwendung im oder am Menschen!
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