Recombinant Human ?-NGF/NGFB Protein (aa 122-23, Human Cells)(Active) (RPES3611)

Recombinant Human ?-NGF/NGFB Protein (aa 122-23, Human Cells)(Active) (RPES3611)
NEU
Artikelnummer Größe Datenblatt Manual SDB Lieferzeit Menge Preis
G-RPES3611.10 10 µg - - -

9 - 20 Werktage*

43,00 €
 
Recombinant Human ?-NGF/NGFB Protein (aa 122-23, Human Cells)(Active) from Assay Genie.... mehr
Produktinformationen "Recombinant Human ?-NGF/NGFB Protein (aa 122-23, Human Cells)(Active) (RPES3611)"
Recombinant Human ?-NGF/NGFB Protein (aa 122-23, Human Cells)(Active) from Assay Genie. Recombinant Human ?-NGF/NGFB Protein (aa 122-23, Human Cells)(Active) is a highly purified recombinant protein produced in Human Cells and for the use in functional assays from Assay Genie.. Protein function: Nerve growth factor is important for the development and maintenance of the sympathetic and sensory nervous systems (PubMed:14976160, PubMed:20978020). Extracellular ligand for the NTRK1 and NGFR receptors, activates cellular signaling cascades to regulate neuronal proliferation, differentiation and survival (PubMed:20978020) (Probable). The immature NGF precursor (proNGF) functions as ligand for the heterodimeric receptor formed by SORCS2 and NGFR, and activates cellular signaling cascades that lead to inactivation of RAC1 and/or RAC2, reorganization of the actin cytoskeleton and neuronal growth cone collapse. In contrast to mature NGF, the precursor form (proNGF) promotes neuronal apoptosis (in vitro). Inhibits metalloproteinase-dependent proteolysis of platelet glycoprotein VI (PubMed:20164177). Binds lysophosphatidylinositol and lysophosphatidylserine between the two chains of the homodimer. The lipid-bound form promotes histamine relase from mast cells, contrary to the lipid-free form. [The UniProt Consortium]
Schlagworte: NGF, NGFB, Beta-NGF, Beta-nerve growth factor
Hersteller: Assay Genie
Hersteller-Nr: RPES3611

Eigenschaften

Konjugat: No
Exprimiert in: Human cells
Ursprungsart: Human
Format: Highly Purified

Datenbank Information

KEGG ID : K02582 | Passende Produkte
UniProt ID : P01138 | Passende Produkte

Handhabung & Sicherheit

Lagerung: -20°C
Versand: +4°C (International: +4°C)
Achtung
Nur für Forschungszwecke und Laboruntersuchungen: Nicht für die Anwendung im oder am Menschen!
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