Recombinant Human LMCD1/Dyxin Protein (His Tag) (RPES3609)

Human LMCD1/Dyxin Recombinant Protein (RPES3609) is a highly pure recombinant protein developed by Assay Genie for use in a range of applications Protein function: Transcriptional cofactor that restricts GATA6 function by inhibiting DNA-binding, resulting in repression of GATA6 transcriptional activation of downstream target genes. Represses GATA6- mediated trans activation of lung- and cardiac tissue-specific promoters. Inhibits DNA-binding by GATA4 and GATA1 to the cTNC promoter. Plays a critical role in the development of cardiac hypertrophy via activation of calcineurin/nuclear factor of activated T-cells signaling pathway. [The UniProt Consortium]