Recombinant Human Interleukin-13/IL-13 (C-6His)

Recombinant Human Interleukin-13/IL-13 (C-6His)
Artikelnummer Größe Datenblatt Manual SDB Lieferzeit Menge Preis
ABE-32-7924-10 10 µg - -

2 - 11 Werktage

485,00 €
ABE-32-7924-50 50 µg - -

2 - 11 Werktage

871,00 €
 
Source: Human Cells. MW :14.3kD. Recombinant Human Interleukin-13 is produced by our Mammalian... mehr
Produktinformationen "Recombinant Human Interleukin-13/IL-13 (C-6His)"
Source: Human Cells. MW :14.3kD. Recombinant Human Interleukin-13 is produced by our Mammalian expression system and the target gene encoding Leu25-Asn146 is expressed with a 6His tag at the C-terminus. Interleukin-13 is also known as IL-13. It is a protein that in humans is encoded by the IL13 gene. Interleukin-13 is an immunoregulatory cytokine produced primarily by activated Th2 cells.It is involved in several stages of B-cell maturation and differentiation. It up-regulates CD23 and MHC class II expression, and promotes IgE isotype switching of B cells. This cytokine down-regulates macrophage activity, thereby inhibits the production of pro-inflammatory cytokines and chemokines. This cytokine is found to be critical to the pathogenesis of allergen-induced asthma but operates through mechanisms independent of IgE and eosinophils. Protein function: Cytokine (PubMed:8096327, PubMed:8097324). Inhibits inflammatory cytokine production (PubMed:8096327). Synergizes with IL2 in regulating interferon-gamma synthesis (PubMed:8096327). May be critical in regulating inflammatory and immune responses (PubMed:8096327, PubMed:8097324). Positively regulates IL31RA expression in macrophages. [The UniProt Consortium]
Hersteller: Abeomics
Hersteller-Nr: 32-7924

Eigenschaften

Konjugat: No

Handhabung & Sicherheit

Lagerung: +20°C
Versand: +20°C (International: +20°C)
Achtung
Nur für Forschungszwecke und Laboruntersuchungen: Nicht für die Anwendung im oder am Menschen!
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