Recombinant Human FBPase 1/FBP1 Protein (Human Cells, His Tag) (RPES3762)

Human FBPase 1/FBP1 Recombinant Protein (RPES3762) is a highly pure recombinant protein developed by Assay Genie for use in a range of applications Protein function: Catalyzes the hydrolysis of fructose 1,6-bisphosphate to fructose 6-phosphate in the presence of divalent cations, acting as a rate-limiting enzyme in gluconeogenesis. Plays a role in regulating glucose sensing and insulin secretion of pancreatic beta-cells. Appears to modulate glycerol gluconeogenesis in liver. Important regulator of appetite and adiposity, increased expression of the protein in liver after nutrient excess increases circulating satiety hormones and reduces appetite-stimulating neuropeptides and thus seems to provide a feedback mechanism to limit weight gain. [The UniProt Consortium]