Recombinant Human EphB4 / HTK Protein (Fc tag)

Recombinant Human EphB4 / HTK Protein (Fc tag)
Artikelnummer Größe Datenblatt Manual SDB Lieferzeit Menge Preis
E-PKSH031739.100 100 µg -

7 - 16 Werktage*

796,00 €
E-PKSH031739.1 1 mg -

7 - 16 Werktage*

5.168,00 €
 
Protein function: Receptor tyrosine kinase which binds promiscuously transmembrane ephrin-B... mehr
Produktinformationen "Recombinant Human EphB4 / HTK Protein (Fc tag)"
Protein function: Receptor tyrosine kinase which binds promiscuously transmembrane ephrin-B family ligands residing on adjacent cells, leading to contact-dependent bidirectional signaling into neighboring cells. The signaling pathway downstream of the receptor is referred to as forward signaling while the signaling pathway downstream of the ephrin ligand is referred to as reverse signaling. Together with its cognate ligand/functional ligand EFNB2 plays a central role in heart morphogenesis and angiogenesis through regulation of cell adhesion and cell migration. EPHB4- mediated forward signaling controls cellular repulsion and segregation form EFNB2-expressing cells. Plays also a role in postnatal blood vessel remodeling, morphogenesis and permeability and is thus important in the context of tumor angiogenesis. [The UniProt Consortium]
Hersteller: Elabscience
Hersteller-Nr: E-PKSH031739

Eigenschaften

Konjugat: No
Spezies-Reaktivität: human
Format: Lyophilized

Handhabung & Sicherheit

Lagerung: -20°C
Versand: +4°C (International: +4°C)
Achtung
Nur für Forschungszwecke und Laboruntersuchungen: Nicht für die Anwendung im oder am Menschen!
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