Recombinant Human Apolipoprotein A1/ApoA1 (C-6His)

Recombinant Human Apolipoprotein A1/ApoA1 (C-6His)
Artikelnummer Größe Datenblatt Manual SDB Lieferzeit Menge Preis
ABE-32-7463-10 10 µg - -

3 - 11 Werktage*

478,00 €
ABE-32-7463-50 50 µg - -

3 - 11 Werktage*

791,00 €
 
Source: Human Cells. MW :30kD. Recombinant Human Apolipoprotein A-I is produced by our Mammalian... mehr
Produktinformationen "Recombinant Human Apolipoprotein A1/ApoA1 (C-6His)"
Source: Human Cells. MW :30kD. Recombinant Human Apolipoprotein A-I is produced by our Mammalian expression system and the target gene encoding Arg19-Gln267 is expressed with a 6His tag at the C-terminus. Apolipoprotein A1 (APOA1) is a secreted protein which belongs to the Apolipoprotein A1/A4/E family. APOA1 is the major protein component of high density lipoprotein (HDL) in plasma. APOA1 plays a critical role in various biological processes, such as Cholesterol metabolism, Lipid metabolism and transport, Steroid metabolism. APOA1 promotes cholesterol efflux from tissues to the liver and thus helps to clear cholesterol from arteries. Defects in this gene resulted in HDL deficiencies, including Tangier disease (TGD), systemic non-neuropathic amyloidosis, premature coronary artery disease, hepatosplenomegaly and progressive muscle wasting and weakness. In addition, ApoA-I is implicated in the anti-endotoxin function of HDL via interaction with lipopolysaccharide or endotoxin. Protein function: Participates in the reverse transport of cholesterol from tissues to the liver for excretion by promoting cholesterol efflux from tissues and by acting as a cofactor for the lecithin cholesterol acyltransferase (LCAT). As part of the SPAP complex, activates spermatozoa motility. [The UniProt Consortium]
Hersteller: Abeomics
Hersteller-Nr: 32-7463

Eigenschaften

Konjugat: No

Handhabung & Sicherheit

Lagerung: +20°C
Versand: +20°C (International: +20°C)
Achtung
Nur für Forschungszwecke und Laboruntersuchungen: Nicht für die Anwendung im oder am Menschen!
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