Prostaglandin F Synthase (human recombinant)

Prostaglandin F Synthase (human recombinant)
Artikelnummer Größe Datenblatt Manual SDB Lieferzeit Menge Preis
Cay10007940-100 100 µg -

5 - 10 Werktage*

475,00 €
 
Human prostaglandin F synthase (PGFS) is a ~37 kDa monomeric protein with high sequence... mehr
Produktinformationen "Prostaglandin F Synthase (human recombinant)"
Human prostaglandin F synthase (PGFS) is a ~37 kDa monomeric protein with high sequence similarity to aldo-keto reductase family members. It exhibits two related primary activities, catalyzing the isomerization of PGH2 to PGF2alpha (PGH2 9,11-endoperoxide reductase activity), as well as the formation of 11beta-PGF2alpha from PGD2 (PGD2 11-ketoreductase activity) in the presence of NADPH. The enzyme also exhibits reductase activities toward carbonyl compounds such at nitroacetophenone, nitrobenzaldehyde, and 9,10-phenanthrene quinine (PQ). Cayman's human recombinant PGFS has been expressed and purified from an E.coli overexpression system. Enzyme activity was determined by monitoring the change in absorbance at 340 nm using PGD2 as the substrate and NADPH as the cofactor (PGD2 11-ketoreductase activity). Synonyms: AKR1C3, Aldo-keto Reductase Family 1 Member C3, 3-alpha-HSD Type II (Brain), 17-beta-HSD 5, PGFS. Purity: >85% estimated by SDS-PAGE. Source: active recombinant C-terminal His-tagged protein expressed in E. coli. Amino Acids: 1-323. MW: 40.4 kDa. Formulation: A solution in 100 mM sodium phosphate, pH 7.2, containing 20% glycerol, 100 mM sodium chloride, and 1 mM EDTA. UniProt Accession #: P42330.
Schlagworte: DD3, DD3, DDH1, DD-3, DD-3, AKR1C3, HA1753, HA1753, 17-beta-HSD 5, 17-beta-HSD 5, 3-alpha-HSD type 2, 3-alpha-HSD type 2, 3-alpha-HSD type II, brain, 3-alpha-HSD type II, brain, Dihydrodiol dehydrogenase 3, Dihydrodiol dehydrogenase 3, Dihydrodiol dehydro
Hersteller: Cayman Chemical
Hersteller-Nr: 10007940

Eigenschaften

Anwendung: Enzyme activity, WB
Konjugat: No
MW: 37 kD
Reinheit: >85% estimated by SDS-PAGE
Format: Solution

Handhabung & Sicherheit

Lagerung: -80°C
Versand: -20°C (International: -80°C)
Signalwort: Warning
GHS-Piktogramme:
H-Sätze: H316, H319
P-Sätze: P264, P280, P305+351+338, P332+313, P337+313
Achtung
Nur für Forschungszwecke und Laboruntersuchungen: Nicht für die Anwendung im oder am Menschen!
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