Polymeric Immunoglobulin Receptor/PIgR Protein(C-Fc) (recombinant human)

Protein Construction: Recombinant Human Polymeric immunoglobulin receptor is produced by our Mammalian expression system and the target gene encoding Lys19-Arg638 is expressed with a Fc tag at the C-terminus. Sequence: Lys19-Arg638. Fusion tag: C-Fc Endotoxin: < 1.0 EU per µg as determined by the LAL method. Apparent Molecular Mass: 120 kDa. Protein function: PIGR binds polymeric IgA and IgM at the basolateral surface of epithelial cells. The complex is then transported across the cell to be secreted at the apical surface. During this process a cleavage occurs that separates the extracellular (known as the secretory component) from the transmembrane segment. Protein function: This receptor binds polymeric IgA and IgM at the basolateral surface of epithelial cells. The complex is then transported across the cell to be secreted at the apical surface. During this process a cleavage occurs that separates the extracellular (known as the secretory component) from the transmembrane segment. [The UniProt Consortium]