Pentraxin 2, Recombinant, Mouse, aa21-224, His-Tag

Pentraxin 2, also known as serum amyloid P-component, is a secreted serum glycoprotein that belongs to the pentraxins family. This family binds calcium-dependent lectin-like manner and is characterized distinctive flattened Beta-jellyroll structure similar to the legume lectins. This protein is a non-fibrillar component, it can interact with DNA and histones. It regulates the solubility of amyloid fibrils and protects them from degradation by proteolytic enzymes and phagocytic cells. This protein is the major acute-phase protein and expression of it is dependent on complement activation, IL-6 and/or IL-1 beta. Source: Recombinant protein corresponding to aa21-224 from mouse Pentraxin2, fused to His-Tag at C-terminal expressed in HEK293.. Molecular Weight: ~24.6kD (210aa), Endotoxin: ~1EU/1ug (LAL), AA Sequence: QTDLKRKVFV FPRESETDHV KLIPHLEKPL QNFTLCFRTY SDLSRSQSLF SYSVKGRDNE LLIYKEKVGE YSLYIGQSKV TVRGMEEYLS PVHLCTTWES SSGIVEFWVN GKPWVKKSLQ REYTVKAPPS IVLGQEQDNY GGGFQRSQSF VGEFSDLYMW DYVLTPQDIL FVYRDSPVNP NILNWQALNY EINGYVVIRP RVWDHHHHHH, Applications: Suitable for use in SDS-PAGE. Other applications not tested. Recommended Dilution: Optimal dilutions to be determined by the researcher. Storage and Stability: May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 6 months after receipt at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.