Mouse Tumor Necrosis Factor-alpha

Mouse Tumor Necrosis Factor-alpha
Artikelnummer Größe Datenblatt Manual SDB Lieferzeit Menge Preis
ABE-32-12323-20 20 µg - -

2 - 11 Werktage

435,00 €
ABE-32-12323-100 100 µg - -

2 - 11 Werktage

740,00 €
Source: Genetically modified E.coli. Predicted MW: Monomer, 17.4 kDa (157 aa)Tumor necrosis... mehr
Produktinformationen "Mouse Tumor Necrosis Factor-alpha"
Source: Genetically modified E.coli. Predicted MW: Monomer, 17.4 kDa (157 aa)Tumor necrosis factor alpha (TNF-alpha) is an inflammatory cytokine secreted by macrophages, monocytes, neutrophils, T cells, and NK-cells following stimulation by bacterial lipopolysaccharide (LPS). TNF-alpha signal activation occurs through two receptors, TNFR1 and TNFR2. TNFR1 is expressed on most cell types, unlike TNFR2, which is expressed mainly on immune cells. TNF-alpha functions to stimulate phagocytosis in macrophages, chemoattract neutrophils, increase insulin resistance, and induce fever. Protein function: Cytokine that binds to TNFRSF1A/TNFR1 and TNFRSF1B/TNFBR. It is mainly secreted by macrophages and can induce cell death of certain tumor cell lines. It is potent pyrogen causing fever by direct action or by stimulation of interleukin-1 secretion and is implicated in the induction of cachexia, Under certain conditions it can stimulate cell proliferation and induce cell differentiation. [The UniProt Consortium]
Hersteller: Abeomics
Hersteller-Nr: 32-12323


Konjugat: No

Handhabung & Sicherheit

Lagerung: -20°C
Versand: °C (International: °C)
Nur für Forschungszwecke und Laboruntersuchungen: Nicht für die Anwendung im oder am Menschen!
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