macaque B7-H4/VTCN1 Protein (His Tag) (recombinant rhesus)

macaque B7-H4/VTCN1 Protein (His Tag) (recombinant rhesus)
Artikelnummer Größe Datenblatt Manual SDB Lieferzeit Menge Preis
E-PKSQ050083.10 10 µg -

7 - 16 Werktage*

109,00 €
E-PKSQ050083.50 50 µg -

7 - 16 Werktage*

248,00 €
 
Activity: Immobilized Human GFRA1-His(Cat: PKSH033670) at 0.5µg/ml(100 µl/well) can bind Human... mehr
Produktinformationen "macaque B7-H4/VTCN1 Protein (His Tag) (recombinant rhesus)"
Activity: Immobilized Human GFRA1-His(Cat: PKSH033670) at 0.5µg/ml(100 µl/well) can bind Human GDNF. The ED50 of GDNF is 14.73ug/ml. Protein Construction: Recombinant Rhesus macaque B7-H4 is produced by our Mammalian expression system and the target gene encoding Phe29-Ala258 is expressed with a 6His tag at the C-terminus. Sequence: Phe29-Ala258. Fusion tag: C-His Endotoxin: < 1.0 EU per µg as determined by the LAL method. Apparent Molecular Mass: 40-60 kDa. Protein function: B7 Homolog 4 (B7-H4) is glycosylated member of the B7 family of immune costimulatory proteins.It is widely expressed, including in kidney, liver, lung, pancreas, placenta, prostate, spleen, testis and thymus. B7-H4 negatively regulates T-cell-mediated immune response by inhibiting T-cell activation, proliferation, cytokine production and development of cytotoxicity. When expressed on the cell surface of tumor macrophages, plays an important role, together with regulatory T-cells (Treg), in the suppression of tumor-associated antigen-specific T-cell immunity. It also involved in promoting epithelial cell transformation.
Schlagworte: V-set domain containing T cell activation inhibitor 1, Recombinant Rhesus macaque B7-H4/VTCN1 Protein (His Tag)
Hersteller: Elabscience
Hersteller-Nr: E-PKSQ050083

Eigenschaften

Konjugat: No
Wirt: Human cells
Spezies-Reaktivität: rhesus
MW: 264 kD
Format: Lyophilized

Handhabung & Sicherheit

Lagerung: -80°C
Versand: 4°C (International: -20°C)
Achtung
Nur für Forschungszwecke und Laboruntersuchungen: Nicht für die Anwendung im oder am Menschen!
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