Leptin, Recombinant, Human (LEP, Leptin Mouse Obesity Homolog, Leptin Precursor Obesity Factor, FLJ9

Leptin, Recombinant, Human (LEP, Leptin Mouse Obesity Homolog, Leptin Precursor Obesity Factor, FLJ9
Artikelnummer Größe Datenblatt Manual SDB Lieferzeit Menge Preis
L1670-17J.200 200 µg - -

1 - 19 Werktage

291,00 €
 
Leptin (Anti-Obesity Protein) is the protein product of the ob (obese) gene in mice and seems to... mehr
Produktinformationen "Leptin, Recombinant, Human (LEP, Leptin Mouse Obesity Homolog, Leptin Precursor Obesity Factor, FLJ9"
Leptin (Anti-Obesity Protein) is the protein product of the ob (obese) gene in mice and seems to be involved in appetite control. The ob gene is expressed in adipose tissue and is thought to regulate the body's fat stores. Mice with the ob/ob genotype also develop a form of diabetes similar to type II (non-insulin dependent) diabetes. Human Leptin is a 16kD protein containing 146 amino acid residues. Source: Recombinant, human Leptin expressed in E. coli. Biological Activity: Human Leptin has been shown to be biologically active in two different mouse obesity models, ob/ob and NZO. Both strains of mice were treated via intraperitoneal injection once daily at a dose of 5ug Leptin/gm of body weight for 7 days. Significant effects on body weight, food consumption, and plasma glucose levels were observed to saline- treated controls. Storage and Stability: Lyophilized powder may be stored at -20°C. Stable for 12 months at -20°C. Reconstitute with sterile HCl. After the protein is completely dissolved, add sterile NaOH to bring the pH to approximately 5.2. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Reconstituted product is stable for 6 months at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
Schlagworte: OB, LEP, Leptin, Obese protein, Obesity factor
Hersteller: United States Biological
Hersteller-Nr: L1670-17J

Eigenschaften

Konjugat: No
Ursprungsart: Human
Format: Highly Purified

Handhabung & Sicherheit

Lagerung: -20°C
Versand: +4°C (International: +4°C)
Achtung
Nur für Forschungszwecke und Laboruntersuchungen: Nicht für die Anwendung im oder am Menschen!
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