K33-linked Di-Ubiquitin (human) (rec.) (untagged)

K33-linked Di-Ubiquitin (human) (rec.) (untagged)
Artikelnummer Größe Datenblatt Manual SDB Lieferzeit Menge Preis
SBB-UP0066-C025 25 µg - -

3 - 9 Werktage*

211,00 €
 
Recombinant Protein. Two enzymatically conjugated human ubiquitin (aa1-76) covalently linked... mehr
Produktinformationen "K33-linked Di-Ubiquitin (human) (rec.) (untagged)"
Recombinant Protein. Two enzymatically conjugated human ubiquitin (aa1-76) covalently linked through an isopeptide bond at K33 residue of one ubiquitin molecule and the C-terminal glycine residue of another ubiquitin molecule and untagged. Source/Host: E. coli. Liquid. In 50mM HEPES pH 7.5. The array of cellular processes initiated and regulated by ubiquitin has been partiallyexplained by the structural diversity of differently linked ubiquitin chains. In a ubiquitin chain, ubiquitin moieties can be conjugated through one of their lysine residues (K6, K11, K27, K29, K33, K48 and K63) or the N-terminal methionine residue (M1), offering countless possibilities to assemble a specific polymer. Ubiquitin molecules can also be modified by other post-translational modifications, including acetylation and phosphorylation, adding another layer of ubiquitin signal regulation and diversification. K33-linked ubiquitin chains are associated with negative regulation of both T-cell antigen receptor (TCR) and AMP-activated protein kinase (AMPK)-related protein kinases K33 linkages have also been implicated in postGolgi protein trafficking. This protein is formed with wild-type human recombinant ubiquitin and linkage-specific enzymes. Ideal for investigating ubiquitin-binding proteins and as substrates for ubiquitin-specific isopeptidases. Reaction conditions will need to be optimized for each specific application.
Schlagworte: Ub2
Hersteller: South Bay Bio
Hersteller-Nr: UP0066

Eigenschaften

Konjugat: No
Wirt: E. coli
Spezies-Reaktivität: human
MW: 17 kD
Reinheit: >95% (SDS-PAGE)
Format: Solution

Handhabung & Sicherheit

Lagerung: -80°C
Versand: -20°C (International: -20°C)
Achtung
Nur für Forschungszwecke und Laboruntersuchungen: Nicht für die Anwendung im oder am Menschen!
Hier kriegen Sie ein Zertifikat
oder , um Analysenzertifikate anzufordern.
Bewertungen lesen, schreiben und diskutieren... mehr
Kundenbewertungen für "K33-linked Di-Ubiquitin (human) (rec.) (untagged)"
Bewertung schreiben
oder , um eine Produktbewertung abzugeben.
Zuletzt angesehen