Human Interleukin-13

Human Interleukin-13
Artikelnummer Größe Datenblatt Manual SDB Lieferzeit Menge Preis
ABE-32-12175-10 10 µg - -

2 - 11 Werktage

435,00 €
ABE-32-12175-100 100 µg - -

2 - 11 Werktage

1.021,00 €
 
Source: Genetically modified E.coli. Predicted MW: Monomer, 12.6 kDa (115 aa) Interleukin 13... mehr
Produktinformationen "Human Interleukin-13"
Source: Genetically modified E.coli. Predicted MW: Monomer, 12.6 kDa (115 aa) Interleukin 13 (IL-13) is a cytokine secreted from type 2 T helper (Th2) cells. IL-13 has overlapping functions with interleukin 4 (IL-4), including the induction of immunoglobulin E (IgE) secretion from B cells, and the inhibition of interleukin 1 beta (IL-1beta ), tumor necrosis factor alpha (TNF-alpha), interleukin 8 (IL-8), and interleukin 6 (IL-6) inflammatory cytokine expression. IL-13 also regulates immune cell inflammation in response to the pathophysiological changes of surrounding non-immune cells. The IL-13 receptor consists of the IL-4Ra and IL-13Ra1 subunits. IL-13 can also bind the IL-13Ra2 receptor with high affinity. IL-13 functions are mediated through the JAK/STAT signaling pathway. Human and mouse IL-13 are cross-reactive. Protein function: Cytokine (PubMed:8096327, PubMed:8097324). Inhibits inflammatory cytokine production (PubMed:8096327). Synergizes with IL2 in regulating interferon-gamma synthesis (PubMed:8096327). May be critical in regulating inflammatory and immune responses (PubMed:8096327, PubMed:8097324). Positively regulates IL31RA expression in macrophages. [The UniProt Consortium]
Hersteller: Abeomics
Hersteller-Nr: 32-12175

Eigenschaften

Konjugat: No

Handhabung & Sicherheit

Lagerung: -20°C
Versand: °C (International: °C)
Achtung
Nur für Forschungszwecke und Laboruntersuchungen: Nicht für die Anwendung im oder am Menschen!
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