CBX2 chromodomain (human recombinant)

CBX2 is a component of the polycomb repressive complex 1 and represses protein expression. The chromodomain regions of CBX2 recognizes histone H3 trimethyl lysine 9 (H3K9me3) or trimethyl lysine 27 (H3K27me3). CBX2 knock-out mice have impaired spleen formation, T cell expansion, and inactivation of the X chromosome, which can be lethal in some cases. This protein product contains the chromodomain region of CBX2.Synonyms: CDCA6, Cell Division Cycle Associated 6, Chromobox Protein Homolog 2 (Drosophila Pc Class), M33, MGC10561, Modifier 3, SRXY5. Purity: >90% estimated by SDS-PAGE. Source: Recombinant N-terminal GST-tagged protein expressed in E. coli. Amino Acids: 2-90. MW: 38.2 kDa. Formulation: (Request formulation change), 50 mM TRIS, pH 8.0, containing 150 mM sodium chloride and 20% glycerol.