Calcineurin B (human, recombinant)

Calcineurin B (human, recombinant)
NEU
Artikelnummer Größe Datenblatt Manual SDB Lieferzeit Menge Preis
Cay34631-20 20 µg - - -

6 - 10 Werktage*

129,00 €
Cay34631-100 100 µg - - -

6 - 10 Werktage*

335,00 €
 
Calcineurin B is the regulatory subunit of calcineurin, a serine/threonine phosphatase with roles... mehr
Produktinformationen "Calcineurin B (human, recombinant)"
Calcineurin B is the regulatory subunit of calcineurin, a serine/threonine phosphatase with roles in T cell activation, cardiac function, learning and memory, apoptosis, and cell cycle regulation. It is encoded by two genes in mammals, PPP3R1, which is expressed in all tissues except the testes, and the testicular-restricted isoform PP3R2. Calcineurin B is a calcium-binding protein that contains four EF-hand calcium-binding sites, and calcium binding to calcineurin B is essential to both the phosphatase activity of calcineurin A and binding of inhibitor complexes to calcineurin. Cayman's Calcineurin B (human, recombinant) protein can be used for binding assays. This protein consists of 187 amino acids and has a calculated molecular weight of 21.4 kDa.Synonyms: Calcineurin Subunit B Type 1, CALNB1, CNA2, CNB, CNB1, PPP3R1, Protein Phosphatase 2B Regulatory Subunit 1, Protein Phosphatase 3 Regulatory Subunit B alpha Isoform 1. Purity: >87% estimated by SDS-PAGE. Endotoxin Testing: <1.0 EU/µg determined by the LAL endotoxin assay. Source: Active recombinant human N-terminal His-tagged calcineurin B expressed in insect cells. Amino Acids: 2-170. MW: 21.4 kDa. Formulation: Lyophilized from sterile 50 mM Tris, pH 8.0, with 100 mM sodium chloride, 2 mM DTT and 10% glycerol. UniProt Accession #: P63098.
Schlagworte: CNA2, PPP3R1, Calcineurin subunit B type 1, Calcineurin subunit B type 1, Protein phosphatase 2B regulatory subunit 1, Protein phosphatase 2B regulatory subunit 1, Protein phosphatase 3 regulatory subunit B alpha isoform 1, Protein phosphatase 3 regulator
Hersteller: Cayman Chemical
Hersteller-Nr: 34631

Eigenschaften

Anwendung: Active protein
Konjugat: No
Exprimiert in: Insect cells
Ursprungsart: Human
MW: 21.4 kD
Reinheit: >87% estimated by SDS-PAGE
Format: Lyophilized

Handhabung & Sicherheit

Lagerung: -80°C
Versand: -80°C (International: -80°C)
Achtung
Nur für Forschungszwecke und Laboruntersuchungen: Nicht für die Anwendung im oder am Menschen!
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