BCMA (mouse):Fc (human, rec.)

(3 x 50µg). The extracellular domain of mouse BCMA (amino acids 1-46) is fused at the C-terminus to the Fc portion of human IgG1. Blocks the binding of mouse BAFF and human APRIL to their receptors BCMA and TACI. Lyophilized. Contains PBS. BCMA is a receptor for BAFF and APRIL. It promotes B cell survival and plays a role in the regulation of humoral immunity. It's downstream signaling is dependent on NF-kappaB and JNK.