Apolipoprotein E, Recombinant, Rabbit, aa19-311, His-Tag (APOE)

Apolipoprotein E, Recombinant, Rabbit, aa19-311, His-Tag (APOE)
NEU
Artikelnummer Größe Datenblatt Manual SDB Lieferzeit Menge Preis
370528.20 20 µg - -

3 - 19 Werktage*

511,00 €
370528.100 100 µg - -

3 - 19 Werktage*

818,00 €
 
Chylomicron remnants and very low density lipoprotein (VLDL) remnants are rapidly removed from... mehr
Produktinformationen "Apolipoprotein E, Recombinant, Rabbit, aa19-311, His-Tag (APOE)"
Chylomicron remnants and very low density lipoprotein (VLDL) remnants are rapidly removed from the circulation by receptor-mediated endocytosis in the liver. Apolipoprotein E, a main apoprotein of the chylomicron, binds to a specific receptor on liver cells and peripheral cells. ApoE is essential for the normal catabolism of triglyceride-rich lipoprotein constituents. The APOE gene is mapped to chromosome 19 in a cluster with APOC1 and APOC2. Defects in apolipoprotein E result in familial dysbetalipoproteinemia, or type III hyperlipoproteinemia (HLP III), in which increased plasma cholesterol and triglycerides are the consequence of impaired clearance of chylomicron and VLDL remnants. Source: Recombinant protein corresponding to aa19-311 from rabbit APOE, fused to His-Tag at N-terminal and Myc-Tag at C-terminal, expressed in E. coli. AA Sequence: QT EQEVEVPEQA RWKAGQPWEL ALGRFWDYLR WVQSLSDQVQ EELLSSQVTQ ELTMLMEETM KEVKAYKSEL EEQLSPMAQE HRARLSKELQ VAGALEADME DVCNRLAQYR GEAQAMLGQS TEELARAFSS HLRKLRKRLL RDAEDLQKRM AVYGAGAREG AERGVSAVRE RLGSRLERGR LRVATVGTLA GRPLRERAQA WGERLRGHLE EVGSRARDRL NEVREQVEEV RVKVEEQAPQ MRLQAEAFQA RLKSWFEPLV EDMQRQWAGL VEKLQAAMPS KAPAAAPIEN Q, Storage and Stability: May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
Schlagworte: APOE, Apo-E, Apolipoprotein E
Hersteller: United States Biological
Hersteller-Nr: 370528

Eigenschaften

Konjugat: No
Format: Purified

Handhabung & Sicherheit

Lagerung: °C
Versand: °C (International: °C)
Achtung
Nur für Forschungszwecke und Laboruntersuchungen: Nicht für die Anwendung im oder am Menschen!
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