Annexin V-EGFP

Elabscience(R) Annexin V-EGFP is developed to identify apoptotic and necrotic cells. Annexin V is a member of the annexin family, which binds to phosphatidylserine (PS) in a calcium-dependent manner. The fluorescent format of this intracellular protein, Annexin V-EGFP, binds specifically to the PS on outer leaflet of cell membrane by flow cytometry or fluorescence microscopy. Cells at different apoptotic stages can be distinguished by using Annexin V and DNA dyes like Propidium Iodide (PI) or 7-AAD.