Aldo-Keto Reductase 1C3/AKR1C3 Protein(C-6His) (recombinant human)

Aldo-Keto Reductase 1C3/AKR1C3 Protein(C-6His) (recombinant human)
Artikelnummer Größe Datenblatt Manual SDB Lieferzeit Menge Preis
E-PKSH032055.10 10 µg -

7 - 16 Werktage*

212,00 €
E-PKSH032055.50 50 µg -

7 - 16 Werktage*

622,00 €
 
Protein Construction: Recombinant Human Aldo-Keto Reductase Family 1 Member C3 is produced by our... mehr
Produktinformationen "Aldo-Keto Reductase 1C3/AKR1C3 Protein(C-6His) (recombinant human)"
Protein Construction: Recombinant Human Aldo-Keto Reductase Family 1 Member C3 is produced by our Mammalian expression system and the target gene encoding Met1-Tyr323 is expressed with a 6His tag at the C-terminus. Sequence: Met 1-Tyr323. Fusion tag: C-6His Endotoxin: < 1.0 EU per µg as determined by the LAL method. Apparent Molecular Mass: 38 kDa. Protein function: AKR1C3, is an enzyme which belongs to the aldo/keto reductase family. It is expressed in many tissues including adrenal gland, brain, kidney, liver, lung, mammary gland, placenta, small intestine, colon, spleen, prostate and testis. AKR1C3 catalyzes the conversion of aldehydes and ketones to alcohols. It catalyzes the reduction of prostaglandin (PG) D2, PGH2 and phenanthrenequinone (PQ) and the oxidation of 9-alpha,11-beta-PGF2 to PGD2,which functions as a bi-directional 3-alpha-, 17-beta- and 20-alpha HSD. It can interconvert active androgens, estrogens and progestins with their cognate inactive metabolites. Protein function: Catalyzes the conversion of aldehydes and ketones to alcohols. Catalyzes the reduction of prostaglandin (PG) D2, PGH2 and phenanthrenequinone (PQ) and the oxidation of 9-alpha,11-beta- PGF2 to PGD2. Functions as a bi-directional 3-alpha-, 17-beta- and 20-alpha HSD. Can interconvert active androgens, estrogens and progestins with their cognate inactive metabolites. Preferentially transforms androstenedione (4-dione) to testosterone. [The UniProt Consortium]
Schlagworte: DD3, DDH1, DD-3, PGFS, AKR1C3, HA1753, EC=1.-.-.-, EC=1.3.1.20, EC=1.1.1.112, 17-beta-HSD 5, 3-alpha-HSD type 2, Indanol dehydrogenase, Prostaglandin F synthase, 3-alpha-HSD type II, brain, Dihydrodiol dehydrogenase 3, Dihydrodiol dehydrogenase type I, Re
Hersteller: Elabscience
Hersteller-Nr: E-PKSH032055

Eigenschaften

Konjugat: No
Wirt: Human cells
Spezies-Reaktivität: human
MW: 37.8 kD
Format: Lyophilized

Handhabung & Sicherheit

Lagerung: -80°C
Versand: +4°C (International: +20°C)
Achtung
Nur für Forschungszwecke und Laboruntersuchungen: Nicht für die Anwendung im oder am Menschen!
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