20S Immunoproteasome (mouse) (untagged)

20S Immunoproteasome (mouse) (untagged)
Artikelnummer Größe Datenblatt Manual SDB Lieferzeit Menge Preis
SBB-PP0083-C050 50 µg - -

3 - 9 Werktage*

414,00 €
 
Protein. Mouse 20S Immunoproteasome. Source: Mouse Spleen. Liquid. In 50mM HEPES pH 7.5, 100mM... mehr
Produktinformationen "20S Immunoproteasome (mouse) (untagged)"
Protein. Mouse 20S Immunoproteasome. Source: Mouse Spleen. Liquid. In 50mM HEPES pH 7.5, 100mM sodium chloride, 1mM TCEP. Purity: >92% (SDS-PAGE). The 20S immunoproteasome is structurally similar to constitutive 26S proteasome. The 20S core of immunoproteasome contains two outer rings composed of alpha-subunits, and two internal 7-subunit containing rings each possessing 3 specific subunits responsible for proteasome catalytic activity. In immunoproteasomes these subunits (beta1, beta2, beta5) are replaced by three inducible subunits: PSMB9, PSMB10 and PSMB8, (beta1i, beta2i, beta5i). These stress-induced subunits allow for the production of MHC-1 associating peptides, which are displayed as antigens on the cell surface. These displayed peptides can then be recognized by immune surveillance CD8 T cells. 20S immunoproteasome is recognized as a strong drug target for autoimmune disease and cancer.
Hersteller: South Bay Bio
Hersteller-Nr: PP0083

Eigenschaften

Konjugat: No
Wirt: Mouse Spleen
MW: 700 kD
Reinheit: >92% (SDS-PAGE)
Format: Liquid

Datenbank Information

Handhabung & Sicherheit

Lagerung: -80°C
Versand: -20°C (International: -20°C)
Achtung
Nur für Forschungszwecke und Laboruntersuchungen: Nicht für die Anwendung im oder am Menschen!
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