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Ac-DEVD-AFC
Artikelnummer: ABD-13401
A fluorogenic substrate for caspase 3. The 7-amido-4-trifluoromethylcoumarin derivatives have better membrane permeability than the 7-amido-4-methylcoumarin derivatives.
| Anwendung: | Caspase-3 substrate |
| CAS | 201608-14-2 |
139,00 €
(Z-DEVD)2-R110
Artikelnummer: ABD-13430
Cleavage of R110 peptides by caspases generates strongly fluorescent R110 that can be monitored fluorimetrically at 510-530 nm with excitation of 488 nm.This R110 substrate is specific for caspases 3 and 7.
| Anwendung: | Caspase-3 substrate, Caspase-7 substrate |
139,00 €
Ac-DEVD-AMC
Artikelnummer: ABD-13402
A fluorogenic substrate for caspase 3, a protease that is rapidly activated when cells are exposed to apoptotic conditions and that cleaves poly(ADP-ribose) polymerase.
| Anwendung: | Caspase-3 substrate |
| CAS | 169332-61-0 |
139,00 €
(Ac-PAL)2R110
Artikelnummer: ABD-13467
The non-fluorescent R110 substrates generate the bright green fluorescent rhodamine 110 product that has Ex/Em = 494/521 nm, and can be easily detected with a FITC filter set. In general, R110 substrates are much more sensitive than the AMC-, AFC- or 4-nitroaniline-based substrates. This R110 substrate is used for...
| Anwendung: | Protease substrate |
139,00 €
PI-3 Kinase Lipid Substrate
Artikelnummer: BPS-40560
PI/PS (4:1, w/w) unilamellar vesicle, prepared with L-alpha-phosphatidylinositol (Liver, Bovine) (sodium salt) and L-alpha-phosphatidylserine (Brain, Porcine) (sodium salt). Lipid monolayer was formed by sonication. Application: Useful as a substrate for PI-3 kinase activity assays and other lipid kinases....
| Anwendung: | PI-3 kinase substrate |
569,00 €
PPACK (hydrochloride)
Artikelnummer: Cay37489-5
PPACK is a synthetic peptide derivative that irreversibly and specifically inhibits thrombin-mediated platelet activation by binding with high affinity to the active site of thrombin (Ki = 0.24 nM). It has been used as an anticoagulant (100 µM) and to study thrombin-mediated fibrin deposition, angiogenesis, and...
| Schlagworte: | D-Phenylalanyl-prolyl-arginyl Chloromethyl Ketone, D-Phe-Pro-Arg-CH2Cl, Pebac,... |
| Anwendung: | Thrombin-mediated platelet activation inhibitor |
| CAS | 82188-90-7 |
| MW: | 523.9 D |
ab 48,00 €
NEU
LL-37 (13-37) (human) (trifluoroacetate salt)
Artikelnummer: Cay36949-1
LL-37 (13-37) is an anticancer peptide fragment of LL-37 (Cay-24461). It inhibits the ATPase activity of ATP-binding cassette transporter 2, subfamily G (ABCG2) when used at a concentration of 1 µM. LL-37 (13-37) induces cytotoxicity in wild-type SW620 cells and SW620 cells overexpressing P-glycoprotein (P-gp), also...
| Schlagworte: | CAP-18, Cathelicidin, FALL-39, hCAP-18, IG-25, LL-13, LL-25,... |
| Anwendung: | LL-37 anticancer peptide fragment |
| MW: | 3043.6 D |
ab 53,00 €
NEU
CXCL9 (74-103) (human) (trifluoroacetate salt)
Artikelnummer: Cay38849-1
Chemokine (C-X-C motif) ligand 9 (CXCL9) (74-103) is a C-terminal fragment of mature CXCL9. It binds to the glycosaminoglycan heparin in a cell-free assay (Kd = 3.1 nM). CXCL9 (74-103) inhibits the binding of CXCL8 or CXCL11 to heparin, as well as chemokine (C-C motif) ligand 2 (CCL2) binding to heparan sulfate, in...
| Schlagworte: | Chemokine (C-X-C motif) Ligand 9 (74-103), MIG30, Monokine Induced by Interferon-gamma (74-103) |
| Anwendung: | CXCL9-derived peptide |
| MW: | 3661.4 D |
ab 66,00 €
NEU
Aureobasidin A
Artikelnummer: Cay39722-10
Aureobasidin A is a cyclic depsipeptide that has been found in A. pullulans and has diverse biological activities. It inhibits inositol phosphorylceramide synthase, an enzyme involved in sphingolipid biosynthesis (Kis = 0.18 and 0.23 for the C. albicans and S. cerevisiae enzymes, respectively). Aureobasidin A also...
| Schlagworte: | Antibiotic R 106I, Basifungin, LY295337, NK 204, R 106-1,... |
| Anwendung: | Bioactive cyclic depsipeptide |
| CAS | 127785-64-2 |
| MW: | 1101.4 D |
ab 218,00 €
NEU
Retatrutide (sodium salt)
Artikelnummer: Cay39747-1
Retatrutide is a triple agonist of the glucagon receptor (GCGR), glucagon-like peptide 1 receptor (GLP-1R), and gastric inhibitory polypeptide receptor (GIP receptor), also known as the glucose-dependent insulinotropic polypeptide receptor. It induces cAMP accumulation in HEK293 cells expressing the human GCGR,...
| Schlagworte: | LY3437943,... |
| Anwendung: | GCGR / GLP-1R / GIPR triple agonist |
| MW: | 4731.3 D |
ab 77,00 €
NEU
PE 22-28 (acetate)
Artikelnummer: Cay39986-1
PE 22-28 is a peptide inhibitor of the two-pore domain potassium channel K2P2.1/TREK1 (IC50 = 0.1 nM in HEK293 cells expressing the human channel) and a fragment of spadin (Cay-36762). It is selective for K2P2.1/TREK1 over K2P10.1 /TREK2, K2P13.1/TRAAK, K2P18.1/TRESK, and K2P3.1/TASK1 in HEK293 cells expressing the...
| Schlagworte: | Gly-Val-Ser-Trp-Gly-Leu-Arg-OH, glycyl-L-valyl-L-seryl-L-tryptophylglycyl-L-leucyl-L-arginine, acetate |
| Anwendung: | K2P2.1/TREK1 peptide inhibitor |
| MW: | 773.9 D |
ab 119,00 €
![[pGlu4]-Myelin Basic Protein Peptide (trifluoroacetate salt)](https://www.biomol.com/media/image/a1/b0/cc/Cay40149-1_200x200.png "[pGlu4]-Myelin Basic Protein Peptide (trifluoroacetate salt)")
[pGlu4]-Myelin Basic Protein Peptide (trifluoroacetate salt)
Artikelnummer: Cay40149-1
[pGlu4]-Myelin basic protein peptide is a substrate for PKC. It is selectively phosphorylated by PKC over PKA and phosphorylase kinase.Formal Name: 5-oxo-L-prolyl-L-lysyl-L-arginyl-L-prolyl-L-seryl-L-glutaminyl-L-arginyl-L-seryl-L-lysyl-L-tyrosyl-L-leucine, trifluoroacetate salt. Synonyms: [pGlu4]-MBP Peptide....
| Schlagworte: | [pGlu4]-MBP Peptide,... |
| Anwendung: | PKC peptide substrate |
| MW: | 1373.6 D |
ab 34,00 €