Prosaptide TX14(A) (trifluoroacetate salt)

Prosaptide TX14(A) (trifluoroacetate salt)
Artikelnummer Größe Datenblatt Manual SDB Lieferzeit Menge Preis
Cay33935-500 500 µg -

6 - 10 Werktage*

130,00 €
Cay33935-1 1 mg -

6 - 10 Werktage*

209,00 €
Cay33935-5 5 mg -

6 - 10 Werktage*

780,00 €
Cay33935-10 10 mg -

6 - 10 Werktage*

1.297,00 €
 
Prosaptide TX14(A) is a peptide fragment of the neurotrophic factor prosaposin and an agonist of... mehr
Produktinformationen "Prosaptide TX14(A) (trifluoroacetate salt)"
Prosaptide TX14(A) is a peptide fragment of the neurotrophic factor prosaposin and an agonist of GPR37L1 and GPR37. It activates ERK signaling in HEK293T cells expressing GPR37L1 or GPR37 (EC50s = 5 and 7 nM, respectively) and inhibits forskolin-induced cAMP production in the same cells. Prosaptide TX14(A) (100 nM) protects primary mouse astrocytes from hydrogen peroxide-induced cell death. It reduces allodynia in a variety of rat peripheral pain models, including models of diabetic neuropathy and sciatic nerve hemiligation when administered at a dose of 4 mg/kg, as well as prevents paw allodynia induced by formalin at 1 mg/kg.Formal Name: L-threonyl-D-alanyl-L-leucyl-L-isoleucyl-L-alpha-aspartyl-L-asparaginyl-L-asparaginyl-L-alanyl-L-threonyl-L-alpha-glutamyl-L-alpha-glutamyl-L-isoleucyl-L-leucyl-L-tyrosine, trifluoroacetate salt. Synonyms: Prosaposin-derived 14-mer Peptide TX14(A). Molecular Formula: C69H110N16O26 . XCF3COOH. Formula Weight: 1579.7. Purity: >98%. Formulation: (Request formulation change), A solid. Solubility: DMF: 1 mg/ml, DMSO: 1 mg/ml. SMILES: OC(C=C1)=CC=C1C[C@@H](C(O)=O)NC([C@H](CC(C)C)NC([C@H]([C@@H](C)CC)NC([C@H](CCC(O)=O)NC([C@H](CCC(O)=O)NC([C@H]([C@H](O)C)NC([C@H](C)NC([C@H](CC(N)=O)NC([C@H](CC(N)=O)NC([C@H](CC(O)=O)NC([C@H]([C@@H](C)CC)NC([C@H](CC(C)C)NC([C@@H](C)NC([C@@H](N)[C@H](O)C)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O.OC(C(F)(F)F)=O. InChi Code: InChI=1S/C69H110N16O26.C2HF3O2/c1-13-31(7)53(66(107)80-41(23-29(3)4)61(102)82-46(69(110)111)25-37-15-17-38(88)18-16-37)83-59(100)40(20-22-50(93)94)75-58(99)39(19-21-49(91)92)76-68(109)55(36(12)87)85-57(98)34(10)73-60(101)43(26-47(70)89)78-62(103)44(27-48(71)90)79-63(104)45(28-51(95)96)81-67(108)54(32(8)14-2)84-64(105)42(24-30(5)6)77-56(97)33(9)74-65(106)52(72)35(11)86,3-2(4,5)1(6)7/h15-18,29-36,39-46,52-55,86-88H,13-14,19-28,72H2,1-12H3,(H2,70,89)(H2,71,90)(H,73,101)(H,74,106)(H,75,99)(H,76,109)(H,77,97)(H,78,103)(H,79,104)(H,80,107)(H,81,108)(H,82,102)(H,83,100)(H,84,105)(H,85,98)(H,91,92)(H,93,94)(H,95,96)(H,110,111),(H,6,7)/t31-,32-,33+,34-,35+,36+,39-,40-,41-,42-,43-,44-,45-,46-,52-,53-,54-,55-,/m0./s1. InChi Key: NWNAHGRGWGVHED-LKMBYFDSSA-N.
Schlagworte: Prosaposin-derived 14-mer Peptide TX14(A), L-threonyl-D-alanyl-L-leucyl-L-isoleucyl-L-alpha-aspartyl-L-asparaginyl-L-asparaginyl-L-alanyl-L-threonyl-L-alpha-glutamyl-L-alpha-glutamyl-L-isoleucyl-L-leucyl-L-tyrosine
Hersteller: Cayman Chemical
Hersteller-Nr: 33935

Eigenschaften

Anwendung: Prosaposin peptide fragment, GPR37L1 / GPR37 agonist
Konjugat: No
MW: 1579.7 D
Formel: C69H110N16O26 . XCF3COOH
Reinheit: >98%
Format: Solid

Datenbank Information

KEGG ID : K04243 | Passende Produkte

Handhabung & Sicherheit

Lagerung: -20°C
Versand: +20°C (International: -20°C)
Achtung
Nur für Forschungszwecke und Laboruntersuchungen: Nicht für die Anwendung im oder am Menschen!
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