Orexin A amide (bovine, human, mouse, rat) (trifluoroacetate salt)

Orexin A amide (bovine, human, mouse, rat) (trifluoroacetate salt)
Artikelnummer Größe Datenblatt Manual SDB Lieferzeit Menge Preis
Cay15073-500 500 µg -

6 - 10 Werktage*

385,00 €
Cay15073-1 1 mg -

6 - 10 Werktage*

650,00 €
Cay15073-5 5 mg -

6 - 10 Werktage*

3.051,00 €
 
Orexin A is a 33 amino acid hypothalamic neuropeptide with a role in appetite regulation,... mehr
Produktinformationen "Orexin A amide (bovine, human, mouse, rat) (trifluoroacetate salt)"
Orexin A is a 33 amino acid hypothalamic neuropeptide with a role in appetite regulation, wakefulness, locomotor activity, hypothalamic-pituitary-adrenal activity, and pain thresholds. Orexin signaling is activated by nutrient depletion, causing an increase in food intake by delaying the signals of satiety. It activates the orexin-1 and -2 receptors with equal affinity (EC50s = 0.09 and 0.06 µM, respectively).Formal Name: 5-oxo-L-prolyl-L-prolyl-L-leucyl-L-prolyl-L-alpha-aspartyl-L-cysteinyl-L-cysteinyl-L-arginyl-L-glutaminyl-L-lysyl-L-threonyl-L-cysteinyl-L-seryl-L-cysteinyl-L-arginyl-L-leucyl-L-tyrosyl-L-a-glutamyl-L-leucyl-L-histidylglycyl-L-alanylglycyl-L-asparaginyl-L-histidyl-L-alanyl-L-alanylglycyl-L-isoleucyl-L-leucyl-L-threonyl-L-leucinamide, cyclic (6->12),(7->14)-bis(disulfide), trifluoroacetate salt. Synonyms: Hypocretin 1, OXA. Molecular Formula: C152H243N47O44S4 . XCF3COOH. Formula Weight: 3561.1. Purity: >95%. Formulation: (Request formulation change), A crystalline solid. Solubility: DMSO: 3 mg/ml, DMSO:PBS (pH 7.2) (1:1): 0.5 mg/ml. SMILES: NC([C@@H](NC([C@@]([H])(NC([C@@H](NC([C@@]([H])(NC(CNC([C@H](C)NC([C@H](C)NC([C@H](CC1=CN=CN1)NC([C@@H](NC(CNC([C@H](C)NC(CNC([C@H](CC2=CN=CN2)NC([C@@H](NC([C@@H](NC([C@@H](NC([C@H](CC3=CC=C(C=C3)O)NC([C@@H](NC([C@@H](NC([C@H](CSSC[C@@H]4N5)NC([C@@H](NC([C@H](CSSC[C@@H](C5=O)NC([C@H](CC(O)=O)NC([C@@H]6CCCN6C([C@@H](NC([C@@H]7CCCN7C(C8NC(CC8)=O)=O)=O)CC(C)C)=O)=O)=O)NC([C@@]([H])(NC([C@@H](NC([C@@H](NC([C@@H](NC4=O)CCCNC(N)=N)=O)CCC(N)=O)=O)CCCCN)=O)[C@H](O)C)=O)=O)CO)=O)=O)CCCNC(N)=N)=O)CC(C)C)=O)=O)CCC(O)=O)=O)CC(C)C)=O)CC(C)C)=O)=O)=O)=O)=O)CC(N)=O)=O)=O)=O)=O)=O)[C@@H](C)CC)=O)CC(C)C)=O)[C@H](O)C)=O)CC(C)C)=O.OC(C(F)(F)F)=O. InChi Code: InChI=1S/C152H243N47O44S4.C2HF3O2/c1-20-76(14)118(146(239)188-96(51-74(10)11)138(231)197-119(80(18)201)147(240)180-92(121(156)214)47-70(2)3)195-115(209)62-166-123(216)78(16)171-124(217)79(17)172-131(224)99(55-84-59-162-69-169-84)186-136(229)100(56-111(155)205)174-114(208)61-165-122(215)77(15)170-113(207)60-167-125(218)98(54-83-58-161-68-168-83)185-134(227)95(50-73(8)9)183-132(225)93(48-71(4)5)182-129(222)90(38-41-116(210)211)179-135(228)97(53-82-32-34-85(203)35-33-82)184-133(226)94(49-72(6)7)181-127(220)88(29-24-44-164-152(159)160)177-140(233)104-64-244-245-65-105-141(234)176-87(28-23-43-163-151(157)158)126(219)178-89(36-39-110(154)204)128(221)175-86(27-21-22-42-153)130(223)196-120(81(19)202)148(241)194-107(142(235)190-103(63-200)139(232)192-104)67-247-246-66-106(143(236)193-105)191-137(230)101(57-117(212)213)187-144(237)108-30-26-46-199(108)150(243)102(52-75(12)13)189-145(238)109-31-25-45-198(109)149(242)91-37-40-112(206)173-91,3-2(4,5)1(6)7/h32-35,58-59,68-81,86-109,118-120,200-203H,20-31,36-57,60-67,153H2,1-19H3,(H2,154,204)(H2,155,205)(H2,156,214)(H,161,168)(H,162,169)(H,165,215)(H,166,216)(H,167,218)(H,170,207)(H,171,217)(H,172,224)(H,173,206)(H,174,208)(H,175,221)(H,176,234)(H,177,233)(H,178,219)(H,179,228)(H,180,240)(H,181,220)(H,182,222)(H,183,225)(H,184,226)(H,185,227)(H,186,229)(H,187,237)(H,188,239)(H,189,238)(H,190,235)(H,191,230)(H,192,232)(H,193,236)(H,194,241)(H,195,209)(H,196,223)(H,197,231)(H,210,211)(H,212,213)(H4,157,158,163)(H4,159,160,164),(H,6,7)/t76-,77-,78-,79-,80+,81+,86-,87-,88-,89-,90-,91?,92-,93-,94-,95-,96-,97-,98-,99-,100-,101-,102-,103-,104-,105-,106-,107-,108-,109-,118-,119-,120-,/m0./s1. InChi Key: WZAWIIMGYTTYRF-GUDKFVGSSA-N. Origin: Synthetic.
Schlagworte: Hypocretin 1, OXA
Hersteller: Cayman Chemical
Hersteller-Nr: 15073

Eigenschaften

Anwendung: HCRTR1/2 Ox1R / Ox2R ligand
Konjugat: No
MW: 3561.1 D
Formel: C152H243N47O44S4 . XCF3COOH
Reinheit: >95%
Format: Crystalline Solid

Handhabung & Sicherheit

Lagerung: -20°C
Versand: +20°C (International: -20°C)
Achtung
Nur für Forschungszwecke und Laboruntersuchungen: Nicht für die Anwendung im oder am Menschen!
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