L-Aspartyl-L-phenylalanine

L-Aspartyl-L-phenylalanine is a dipeptide inhibitor of angiotensin-converting enzyme (ACE) and a metabolite of the synthetic non-caloric sweetener aspartame (Cay-26089). It is formed from aspartame by intestinal intracellular esterases. L-Aspartyl-L-phenylalanine inhibits ACE with a Ki value of 11 µM for the rabbit enzyme. Serum levels of L-aspartyl-L-phenylalanine are positively associated with pancreatic ductal adenocarcinoma.Formal Name: L-alpha-aspartyl-L-phenylalanine. CAS Number: 13433-09-5. Synonyms: alpha-Aspartylphenylalanine, Asp-Phe. Molecular Formula: C13H16N2O5. Formula Weight: 280.3. Purity: >98%. Formulation: (Request formulation change), A solid. Solubility: DMSO: 5 mg/ml, DMSO:PBS (pH 7.2) (1:2): 0.3 mg/ml. SMILES: OC(C[C@H](N)C(N[C@H](C(O)=O)CC1=CC=CC=C1)=O)=O. InChi Code: InChI=1S/C13H16N2O5/c14-9(7-11(16)17)12(18)15-10(13(19)20)6-8-4-2-1-3-5-8/h1-5,9-10H,6-7,14H2,(H,15,18)(H,16,17)(H,19,20)/t9-,10-/m0/s1. InChi Key: YZQCXOFQZKCETR-UWVGGRQHSA-N.