Iberiotoxin (trifluoroacetate salt)

Iberiotoxin (trifluoroacetate salt)
Artikelnummer Größe Datenblatt Manual SDB Lieferzeit Menge Preis
Cay14608-100 100 µg -

6 - 10 Werktage*

448,00 €
 
Iberiotoxin, a peptide purified from venom of the scorpion B. tamulus, is a selective blocker of... mehr
Produktinformationen "Iberiotoxin (trifluoroacetate salt)"
Iberiotoxin, a peptide purified from venom of the scorpion B. tamulus, is a selective blocker of large-conductance calcium-activated potassium channels (KCa1.1/BKCa). In single channel recordings, iberiotoxin can reversibly block outward currents mediated by KCa1.1 in excised membrane patches from bovine aortic smooth muscle with an IC50 value of 250 pM. It is also a noncompetitive, partial inhibitor of charybdotoxin binding in bovine aortic sarcolemmal membrane vesicles (Ki = 250 pM).CAS Number: 182897-30-9. Formula Weight: 4230.9. Purity: >95%. Formulation: (Request formulation change), A solid. Solubility: Water: Soluble. SMILES: [H]N(C(C1CCC(N1)=O)=O)[C@H](C(N[C@]([C@@H](C)O)([H])C(N[C@H](C(N[C@@H](C(C)C)C(N[C@H](C(N[C@H](C(N[C@@H](CO)C(N[C@@H](C(C)C)C(N[C@@H](CO)C(N[C@@H](CCCCN)C(N[C@@H](CCC(O)=O)C(N[C@H](C(N[C@H](C(N[C@@H](CO)C(N[C@@H](C(C)C)C(N[C@H](C(N[C@@H](CCCCN)C(N[C@H](C(N[C@@H](CC(C)C)C(N[C@H](C(NCC(N[C@@H](C(C)C)C(N[C@H](C(N[C@@H](CCCNC(N)=N)C(NCC(N[C@@H](CCCCN)C2=O)=O)=O)=O)CC(O)=O)=O)=O)=O)CC3=CC=CC=C3)=O)=O)CC(O)=O)=O)=O)CSSC[C@H](N4)C(N[C@H](C(N[C@@H](CCC(N)=O)C(O)=O)=O)CC5=CC=C(O)C=C5)=O)=O)=O)=O)CC6=CNC7=C6C=CC=C7)=O)CSSC[C@H](N8)C(N[C@@H](CCCNC(N)=N)C4=O)=O)=O)=O)=O)=O)=O)=O)CSSC[C@H](N2)C(N[C@H](C(NCC(N[C@@H](CCCCN)C(N[C@@H](CCCCN)C8=O)=O)=O)=O)CCSC)=O)=O)CC(O)=O)=O)=O)CC(O)=O)=O)=O)CC9=CC=CC=C9.FC(F)(C(O)=O)F. InChi Code: InChI=1S/C179H274N50O55S7.C2HF3O2/c1-87(2)65-111-155(261)208-112(66-93-33-15-13-16-34-93)146(252)195-77-133(239)225-139(88(3)4)172(278)213-117(71-136(244)245)158(264)199-100(44-31-62-190-178(186)187)144(250)193-75-131(237)198-102(40-22-27-58-181)148(254)219-124-82-287-290-85-127(223-160(266)118(72-137(246)247)214-173(279)140(89(5)6)226-162(268)119(73-138(248)249)215-176(282)143(92(11)233)229-161(267)114(67-94-35-17-14-18-36-94)209-153(259)107-51-54-130(236)196-107)171(277)217-122(80-232)165(271)227-141(90(7)8)174(280)218-120(78-230)163(269)201-103(41-23-28-59-182)149(255)204-108(52-55-134(240)241)154(260)222-126-84-288-286-81-123(220-151(257)105(43-25-30-61-184)200-147(253)101(39-21-26-57-180)197-132(238)76-194-145(251)109(56-64-285-12)205-167(124)273)166(272)203-106(45-32-63-191-179(188)189)152(258)221-125(169(275)210-113(68-95-46-48-97(234)49-47-95)156(262)206-110(177(283)284)50-53-129(185)235)83-289-291-86-128(168(274)202-104(42-24-29-60-183)150(256)212-116(70-135(242)243)159(265)207-111)224-175(281)142(91(9)10)228-164(270)121(79-231)216-157(263)115(211-170(126)276)69-96-74-192-99-38-20-19-37-98(96)99,3-2(4,5)1(6)7/h13-20,33-38,46-49,74,87-92,100-128,139-143,192,230-234H,21-32,39-45,50-73,75-86,180-184H2,1-12H3,(H2,185,235)(H,193,250)(H,194,251)(H,195,252)(H,196,236)(H,197,238)(H,198,237)(H,199,264)(H,200,253)(H,201,269)(H,202,274)(H,203,272)(H,204,255)(H,205,273)(H,206,262)(H,207,265)(H,208,261)(H,209,259)(H,210,275)(H,211,276)(H,212,256)(H,213,278)(H,214,279)(H,215,282)(H,216,263)(H,217,277)(H,218,280)(H,219,254)(H,220,257)(H,221,258)(H,222,260)(H,223,266)(H,224,281)(H,225,239)(H,226,268)(H,227,271)(H,228,270)(H,229,267)(H,240,241)(H,242,243)(H,244,245)(H,246,247)(H,248,249)(H,283,284)(H4,186,187,190)(H4,188,189,191),(H,6,7)/t92-,100+,101+,102+,103+,104+,105+,106+,107?,108+,109+,110+,111+,112+,113+,114+,115+,116+,117+,118+,119+,120+,121+,122+,123+,124+,125+,126+,127+,128+,139+,140+,141+,142+,143+,/m1./s1. InChi Key: ZDGJIMQFDSPUJP-XYHSBZLHSA-N.
Schlagworte: 4-L-aspartic acid-6-L-aspartic acid-8-L-serine-9-L-valine-18-L-lysine-19-L-aspartic acid-21-L-phenylalanine-22-glycine-23-L-valine-24-L-aspartic acid-30-glycine-37-L-glutamine-charybdotoxin
Hersteller: Cayman Chemical
Hersteller-Nr: 14608

Eigenschaften

Anwendung: BKCa blocker
Konjugat: No
MW: 4230.9 D
Reinheit: >95%
Format: Solid

Datenbank Information

CAS : 182897-30-9| Passende Produkte
KEGG ID : K04936 | Passende Produkte

Handhabung & Sicherheit

Lagerung: -20°C
Versand: +20°C (International: -20°C)
Signalwort: Danger
GHS-Piktogramme:
H-Sätze: H300, H310, H330
P-Sätze: P260, P262, P264, P270, P271, P280, P284, P320, P321, P330, P301+P310, P302+P352, P304+P340, P361+P364, P405, P403+P233, P501
Achtung
Nur für Forschungszwecke und Laboruntersuchungen: Nicht für die Anwendung im oder am Menschen!
Hier kriegen Sie ein Zertifikat
oder , um Analysenzertifikate anzufordern.
Bewertungen lesen, schreiben und diskutieren... mehr
Kundenbewertungen für "Iberiotoxin (trifluoroacetate salt)"
Bewertung schreiben
oder , um eine Produktbewertung abzugeben.
Zuletzt angesehen