Histone H3K36Me3 (26-46)-K-biotin (trifluoroacetate salt)

Histone H3K36Me3 (26-46)-K-biotin is a peptide fragment of histone H3 that contains a serine-to-alanine substitution at position 29 and corresponds to amino acid residues 27-47 of the human histone H3.1 and H3.2 sequences. It is trimethylated at lysine 36 and biotinylated via a C-terminal lysine linker. Histone H3K36Me3 (26-46)-K-biotin corresponds directly to amino acid residues 27-47 of the yeast H3.1 sequence in S. octosporus and S. pombe and of the plant pathogenic fungus histone sequence in P. striiformis.Formal Name: L-arginyl-L-lysyl-L-alanyl-L-alanyl-L-prolyl-L-alanyl-L-threonylglyclglycyl-L-valyl-L-6-(trimethylammonio)-L-norleucyl-L-lysyl-L-prolyl-L-histidyl-L-arginyl-L-tyrosyl-L-arginyl-L-prolylglycyl-L-threonyl-L-valyl-L-lysine-biotin, trifluoroacetate salt. Synonyms: Histone H3 (26-46) (Lys36me3), [Lys(Me3)36]-Histone H3 (26-46)-K(Biotin), RKAAPATGGV-K(Me3)-KPHRYRPGTV-K(biotin). Molecular Formula: C118H199N39O28S . XCF3COOH. Formula Weight: 2644.2. Purity: >95%. Formulation: (Request formulation change), A solid. Solubility: Water: 1 mg/ml. SMILES: C[N+](CCCC[C@H](NC([C@@H](NC(CNC(CNC([C@@]([H])(NC([C@H](C)NC([C@@H]1CCCN1C([C@H](C)NC([C@H](C)NC([C@@H](NC([C@@H](N[H])CCCNC(N)=N)=O)CCCCN)=O)=O)=O)=O)=O)[C@H](O)C)=O)=O)=O)C(C)C)=O)C(N[C@H](C(N2CCC[C@H]2C(N[C@@H](CC3=CN=CN3)C(N[C@H](C(N[C@@H](CC4=CC=C(C=C4)O)C(N[C@H](C(N5CCC[C@H]5C(NCC(N[C@]([H])(C(N[C@H](C(N[C@H](C([O-])=O)CCCCNC(CCCC[C@@H]6SC[C@@]([H])([C@@]6(N7)[H])NC7=O)=O)=O)C(C)C)=O)[C@H](O)C)=O)=O)=O)CCCNC(N)=N)=O)=O)CCCNC(N)=N)=O)=O)=O)CCCCN)=O)(C)C.O=C(O)C(F)(F)F. InChi Code: InChI=1S/C118H199N39O28S.C2HF3O2/c1-63(2)91(149-89(163)59-133-88(162)58-135-107(176)93(68(8)158)152-97(166)66(6)138-105(174)84-37-27-51-154(84)111(180)67(7)139-96(165)65(5)137-99(168)74(30-15-19-45-119)140-98(167)73(121)29-23-48-130-115(122)123)108(177)142-75(31-18-22-54-157(10,11)12)100(169)143-77(32-16-20-46-120)112(181)156-53-28-38-85(156)106(175)147-81(56-71-57-128-62-136-71)103(172)141-76(34-24-49-131-116(124)125)101(170)146-80(55-70-41-43-72(160)44-42-70)102(171)144-78(35-25-50-132-117(126)127)113(182)155-52-26-36-83(155)104(173)134-60-90(164)150-94(69(9)159)110(179)151-92(64(3)4)109(178)145-79(114(183)184)33-17-21-47-129-87(161)40-14-13-39-86-95-82(61-186-86)148-118(185)153-95,3-2(4,5)1(6)7/h41-44,57,62-69,73-86,91-95,158-159H,13-40,45-56,58-61,119-121H2,1-12H3,(H35-,122,123,124,125,126,127,128,129,130,131,132,133,134,135,136,137,138,139,140,141,142,143,144,145,146,147,148,149,150,151,152,153,160,161,162,163,164,165,166,167,168,169,170,171,172,173,174,175,176,177,178,179,183,184,185),(H,6,7)/t65-,66-,67-,68+,69+,73-,74-,75-,76-,77-,78-,79-,80-,81-,82-,83-,84-,85-,86-,91-,92-,93-,94-,95-,/m0./s1. InChi Key: UTZRHYCOYOJTGF-PSXDUKLRSA-N.