Histone H3K14Ac (1-19) (human, mouse, rat, porcine, bovine) (trifluoroacetate salt)

Histone H3K14Ac (1-19) is a peptide fragment of histone H3 that corresponds to amino acid residues 2-20 of the human histone H3 sequence. Acetylation of H3K14 is associated with transcriptional activation and is required for trimethylation of H3K4. Histone H3K14Ac (1-19) has been used to determine substrate specificity of yeast Hst2 and human SIRT2, which are Silent information regular 2 (Sir2) family enzymes.Formal Name: L-alanyl-L-arginyl-L-threonyl-L-lysyl-L-glutaminyl-L-threonyl-L-alanyl-L-arginyl-L-lysyl-L-seryl-L-threonylglycylglycyl-N6-acetyl-L-lysyl-L-alanyl-L-prolyl-L-arginyl-L-lysyl-L-glutamine, trifluoroacetate salt. Synonyms: ARTKQTARKSTGG-K(Ac)-APRKQ, [Lys(Ac)14]-Histone H3 (1-19), Histone H3 (Lys14ac). Molecular Formula: C87H158N34O27 . XCF3COOH. Formula Weight: 2112.4. Purity: >95%. Formulation: (Request formulation change), A solid. Solubility: Water: 1 mg/ml. SMILES: [H]N[C@H](C(N[C@@H](CCCNC(N)=N)C(N[C@]([C@@H](C)O)([H])C(N[C@@H](CCCCN)C(N[C@@H](CCC(N)=O)C(N[C@]([C@@H](C)O)([H])C(N[C@H](C(N[C@@H](CCCNC(N)=N)C(N[C@@H](CCCCN)C(N[C@@H](CO)C(N[C@]([C@@H](C)O)([H])C(NCC(NCC(N[C@@H](CCCCNC(C)=O)C(N[C@H](C(N1CCC[C@H]1C(N[C@@H](CCCNC(N)=N)C(N[C@@H](CCCCN)C(N[C@@H](CCC(N)=O)C(O)=O)=O)=O)=O)=O)C)=O)=O)=O)=O)=O)=O)=O)=O)C)=O)=O)=O)=O)=O)=O)C.O=C(O)C(F)(F)F. InChi Code: InChI=1S/C87H158N34O27.C2HF3O2/c1-43(91)68(131)109-56(26-18-38-103-87(98)99)76(139)120-67(48(6)125)82(145)115-53(22-10-14-34-90)71(134)113-57(28-30-61(92)127)77(140)119-66(47(5)124)81(144)106-44(2)69(132)110-54(24-16-36-101-85(94)95)72(135)112-52(21-9-13-33-89)75(138)117-59(42-122)78(141)118-65(46(4)123)80(143)105-40-63(129)104-41-64(130)108-50(23-11-15-35-100-49(7)126)70(133)107-45(3)83(146)121-39-19-27-60(121)79(142)114-55(25-17-37-102-86(96)97)73(136)111-51(20-8-12-32-88)74(137)116-58(84(147)148)29-31-62(93)128,3-2(4,5)1(6)7/h43-48,50-60,65-67,122-125H,8-42,88-91H2,1-7H3,(H2,92,127)(H2,93,128)(H,100,126)(H,104,129)(H,105,143)(H,106,144)(H,107,133)(H,108,130)(H,109,131)(H,110,132)(H,111,136)(H,112,135)(H,113,134)(H,114,142)(H,115,145)(H,116,137)(H,117,138)(H,118,141)(H,119,140)(H,120,139)(H,147,148)(H4,94,95,101)(H4,96,97,102)(H4,98,99,103),(H,6,7)/t43-,44-,45-,46+,47+,48+,50-,51-,52-,53-,54-,55-,56-,57-,58-,59-,60-,65-,66-,67-,/m0./s1. InChi Key: UQFRQINOBDTQHC-QRLPTWODSA-N.