Histone H3 (21-44)-GK-biotin amide (trifluoroacetate salt)

Histone H3 (21-44)-GK-biotin amide (trifluoroacetate salt)
Artikelnummer Größe Datenblatt Manual SDB Lieferzeit Menge Preis
Cay27762-250 250 µg -

6 - 10 Werktage*

245,00 €
 
Histone H3 (21-44)-GK-biotin is a peptide fragment of histone H3 that corresponds to amino acid... mehr
Produktinformationen "Histone H3 (21-44)-GK-biotin amide (trifluoroacetate salt)"
Histone H3 (21-44)-GK-biotin is a peptide fragment of histone H3 that corresponds to amino acid residues 22-45 of the human histone H3.3 sequence and is biotinylated via a C-terminal GK linker. Unlike histone H3.1 and H3.2, the histone H3.3 variant contains a serine residue at position 31 that is phosphorylated during late prometaphase and metaphase of mitosis. Histone H3 (21-44) also contains lysine residues at positions 23, 27, and 36 that are subject to methylation and acetylation, all of which have a role in the regulation of gene expression, and a serine residue at position 28 that is subject to phosphorylation during mitosis.Formal Name: L-alanyl-L-threonyl-L-lysyl-L-alanyl-L-alanyl-L-arginyl-L-lysyl-L-seryl-L-alanyl-L-prolyl-L-seryl-L-threonylglycylglycyl-L-valy-L-lysyl-L-lysyl-L-prolyl-L-histidyl-L-arginyl-L-tyrosyl-L-arginyl-L-proylglycylglycyl-L-lysine-biotin amide, trifluoroacetate salt. Synonyms: ATKAARKSAPSTGGVKKPHRYRPG-GK(Biotin)-NH2, Histone H3 (21-44). Molecular Formula: C127H215N45O33S . XCF3COOH. Formula Weight: 2932.4. Purity: >95%. Formulation: (Request formulation change), A solid. Solubility: Water: soluble. SMILES: O=C(O)C(F)(F)F.O=C(NCCCC[C@@H](C(N)=O)NC(CNC(CNC([C@@H]1CCCN1C([C@H](CCCNC(N)=N)NC([C@@H](NC([C@H](CCCNC(N)=N)NC([C@@H](NC([C@@H]2CCCN2C([C@H](CCCCN)NC([C@H](CCCCN)NC([C@H](C(C)C)NC(CNC(CNC([C@@]([C@@H](C)O)([H])NC([C@H](CO)NC([C@@H]3CCCN3C([C@@H](NC([C@H](CO)NC([C@H](CCCCN)NC([C@H](CCCNC(N)=N)NC([C@@H](NC([C@@H](NC([C@H](CCCCN)NC([C@@]([C@@H](C)O)([H])NC([C@@H](N[H])C)=O)=O)=O)C)=O)C)=O)=O)=O)=O)C)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)CC4=CN=CN4)=O)=O)CC5=CC=C(O)C=C5)=O)=O)=O)=O)=O)CCCC[C@@H]6SC[C@@](N7)([H])[C@]6([H])NC7=O. InChi Code: InChI=1S/C127H215N45O33S.C2HF3O2/c1-66(2)98(166-97(182)61-146-95(180)59-148-118(199)99(71(7)175)168-114(195)87(63-174)164-117(198)90-36-25-52-170(90)121(202)70(6)152-113(194)86(62-173)163-110(191)78(29-12-17-45-129)155-107(188)80(32-21-49-142-124(134)135)154-105(186)69(5)150-104(185)68(4)151-106(187)77(28-11-16-44-128)158-120(201)100(72(8)176)167-103(184)67(3)132)119(200)157-79(30-13-18-46-130)108(189)159-82(31-14-19-47-131)122(203)172-54-26-37-91(172)116(197)162-85(56-74-57-140-65-149-74)112(193)156-81(33-22-50-143-125(136)137)109(190)161-84(55-73-40-42-75(177)43-41-73)111(192)160-83(34-23-51-144-126(138)139)123(204)171-53-24-35-89(171)115(196)147-58-94(179)145-60-96(181)153-76(102(133)183)27-15-20-48-141-93(178)39-10-9-38-92-101-88(64-206-92)165-127(205)169-101,3-2(4,5)1(6)7/h40-43,57,65-72,76-92,98-101,173-177H,9-39,44-56,58-64,128-132H2,1-8H3,(H2,133,183)(H,140,149)(H,141,178)(H,145,179)(H,146,180)(H,147,196)(H,148,199)(H,150,185)(H,151,187)(H,152,194)(H,153,181)(H,154,186)(H,155,188)(H,156,193)(H,157,200)(H,158,201)(H,159,189)(H,160,192)(H,161,190)(H,162,197)(H,163,191)(H,164,198)(H,166,182)(H,167,184)(H,168,195)(H4,134,135,142)(H4,136,137,143)(H4,138,139,144)(H2,165,169,205),(H,6,7)/t67-,68-,69-,70-,71+,72+,76-,77-,78-,79-,80-,81-,82-,83-,84-,85-,86-,87-,88-,89-,90-,91-,92-,98-,99-,100-,101-,/m0./s1. InChi Key: IMKVLPOPWVIAMY-JVIXSJCGSA-N.
Schlagworte: ATKAARKSAPSTGGVKKPHRYRPG-GK(Biotin)-NH2, Histone H3 (21-44), L-alanyl-L-threonyl-L-lysyl-L-alanyl-L-alanyl-L-arginyl-L-lysyl-L-seryl-L-alanyl-L-prolyl-L-seryl-L-threonylglycylglycyl-L-valy-L-lysyl-L-lysyl-L-prolyl-L-histidyl-L-arginyl-L-tyrosyl-L-arginyl-
Hersteller: Cayman Chemical
Hersteller-Nr: 27762

Eigenschaften

Anwendung: Biotinylated histone H3 peptide fragment
Konjugat: No
MW: 2932.4 D
Formel: C127H215N45O33S . XCF3COOH
Reinheit: >95%
Format: Solid

Handhabung & Sicherheit

Lagerung: -20°C
Versand: +20°C (International: -20°C)
Achtung
Nur für Forschungszwecke und Laboruntersuchungen: Nicht für die Anwendung im oder am Menschen!
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