Histone H3 (1-18)-WC amide (trifluoroacetate salt)

Histone H3 (1-18)-WC amide is an N-terminal peptide fragment of histone H3 that corresponds to amino acid residues 2-19 of the human histone H3 sequence and also contains a tryptophan and cysteine at its C-terminus. Histone H3 (1-18)-WC amide contains lysine residues at positions 4 and 9 that are subject to methylation and acetylation and a serine residue at position 10 that is subject to phosphorylation, all of which have a role in the regulation of gene expression. Histone H3 (1-18)-WC amide contains a C-terminal cysteine residue that is commonly added to peptides or proteins to facilitate conjugation.Formal Name: L-alanyl-L-arginyl-L-threonyl-L-lysyl-L-glutaminyl-L-threonyl-L-alanyl-L-arginyl-L-lysyl-L-seryl-L-threonylglycylglycyl-L-lysyl-L-alanyl-L-prolyl-L-arginyl-L-lysyl-L-tryptophyl-L-cysteinamide, trifluoroacetate salt. Synonyms: ARTKQTARKSTGGKAPRKWC-NH2. Molecular Formula: C94H164N36O25S . XCF3COOH. Formula Weight: 2230.6. Purity: >95%. Formulation: (Request formulation change), A crystalline solid. Solubility: Water: 1 mg/ml. SMILES: O=C(O)C(F)(F)F.NC([C@@H](NC([C@@H](NC([C@H](CCCCN)NC([C@H](CCCNC(N)=N)NC([C@@H]1CCCN1C([C@@H](NC([C@H](CCCCN)NC(CNC(CNC([C@@]([C@@H](C)O)([H])NC([C@H](CO)NC([C@H](CCCCN)NC([C@H](CCCNC(N)=N)NC([C@@H](NC([C@@]([C@@H](C)O)([H])NC([C@H](CCC(N)=O)NC([C@H](CCCCN)NC([C@@]([C@@H](C)O)([H])NC([C@H](CCCNC(N)=N)NC([C@@H](N[H])C)=O)=O)=O)=O)=O)=O)C)=O)=O)=O)=O)=O)=O)=O)=O)C)=O)=O)=O)=O)CC2=CNC3=C2C=CC=C3)=O)CS)=O. InChi Code: InChI=1S/C94H164N36O25S.C2HF3O2/c1-47(99)75(139)117-62(29-19-39-110-94(106)107)83(147)129-73(52(6)134)90(154)123-59(26-12-16-36-98)78(142)121-63(31-32-68(100)135)84(148)128-72(51(5)133)89(153)114-48(2)76(140)118-60(27-17-37-108-92(102)103)79(143)120-58(25-11-15-35-97)82(146)125-65(45-131)86(150)127-71(50(4)132)88(152)113-43-69(136)112-44-70(137)116-56(23-9-13-33-95)77(141)115-49(3)91(155)130-40-20-30-67(130)87(151)122-61(28-18-38-109-93(104)105)80(144)119-57(24-10-14-34-96)81(145)124-64(85(149)126-66(46-156)74(101)138)41-53-42-111-55-22-8-7-21-54(53)55,3-2(4,5)1(6)7/h7-8,21-22,42,47-52,56-67,71-73,111,131-134,156H,9-20,23-41,43-46,95-99H2,1-6H3,(H2,100,135)(H2,101,138)(H,112,136)(H,113,152)(H,114,153)(H,115,141)(H,116,137)(H,117,139)(H,118,140)(H,119,144)(H,120,143)(H,121,142)(H,122,151)(H,123,154)(H,124,145)(H,125,146)(H,126,149)(H,127,150)(H,128,148)(H,129,147)(H4,102,103,108)(H4,104,105,109)(H4,106,107,110),(H,6,7)/t47-,48-,49-,50+,51+,52+,56-,57-,58-,59-,60-,61-,62-,63-,64-,65-,66-,67-,71-,72-,73-,/m0./s1. InChi Key: VWIAIWJUGRMOLI-BIGQDSNESA-N.