GHK-Cu (acetate)

GHK-Cu (acetate)
Artikelnummer Größe Datenblatt Manual SDB Lieferzeit Menge Preis
Cay28259-25 25 mg -

6 - 10 Werktage*

43,00 €
Cay28259-50 50 mg -

6 - 10 Werktage*

68,00 €
Cay28259-100 100 mg -

6 - 10 Werktage*

92,00 €
Cay28259-250 250 mg -

6 - 10 Werktage*

187,00 €
 
GHK-Cu is a complex of the tripeptide Gly-His-Lys and a copper(II) ion that has wound healing and... mehr
Produktinformationen "GHK-Cu (acetate)"
GHK-Cu is a complex of the tripeptide Gly-His-Lys and a copper(II) ion that has wound healing and anti-inflammatory activities. It increases proliferation and the levels of collagen and secreted pro-matrix metalloproteinase-2 (MMP-2) in isolated human fibroblasts when used at a concentration of 1 nM. GHK-Cu (2 mg) increases levels of collagen and glycosaminoglycans (GAGs) and the expression of decorin in the wound tissue of rats. It decreases LPS-induced increases in the levels of reactive oxygen species (ROS), IL-6, and TNF-alpha in RAW 264.7 cells when used at a concentration of 10 µM. GHK-Cu (10 µg/g) prevents LPS-induced decreases in lung superoxide dismutase (SOD) activity and glutathione (GSH) levels and reduces LPS-induced increases in the number of cells and the level of total protein in bronchoalveolar lavage fluid (BALF) in a mouse model of acute lung injury.Formal Name: [glycyl-kappaN-L-histidyl-kappaN,kappaN3-L-lysinato(2-)]-copper, monoacetate. CAS Number: 300801-03-0. Synonyms: Gly-His-Lys-Cu(II). Molecular Formula: C14H22CuN6O4 . C2H4O2. Formula Weight: 462.0. Purity: >95%. Formulation: (Request formulation change), A solid. Solubility: PBS (pH 7.2): 5 mg/ml. SMILES: CC(O)=O.O=C([C@H]1[N-](C2=O)[Cu+2]([NH2]C2)[N]3=CNC=C3C1)N[C@H](C([O-])=O)CCCCN. InChi Code: InChI=1S/C14H24N6O4.C2H4O2.Cu/c15-4-2-1-3-10(14(23)24)20-13(22)11(19-12(21)6-16)5-9-7-17-8-18-9,1-2(3)4,/h7-8,10-11H,1-6,15-16H2,(H4,17,18,19,20,21,22,23,24),1H3,(H,3,4),/q,,+2/p-2/t10-,11-,,/m0../s1. InChi Key: NOIHSRSQDMJJFH-ULEGLUPFSA-L.
Schlagworte: Gly-His-Lys-Cu(II), [glycyl-kappaN-L-histidyl-kappaN,kappaN3-L-lysinato(2-)]-copper, monoacetate
Hersteller: Cayman Chemical
Hersteller-Nr: 28259

Eigenschaften

Anwendung: Wound healing, antiinflammatory tripeptide copper(II) ion complex
Konjugat: No
MW: 462 D
Formel: C14H22CuN6O4 . C2H4O2
Reinheit: >95%
Format: Solid

Datenbank Information

CAS : 300801-03-0| Passende Produkte

Handhabung & Sicherheit

Lagerung: -20°C
Versand: +20°C (International: -20°C)
Achtung
Nur für Forschungszwecke und Laboruntersuchungen: Nicht für die Anwendung im oder am Menschen!
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