Deslorelin (acetate)

Deslorelin (acetate)
Artikelnummer Größe Datenblatt Manual SDB Lieferzeit Menge Preis
Cay34041-5 5 mg -

6 - 10 Werktage*

112,00 €
Cay34041-10 10 mg -

6 - 10 Werktage*

200,00 €
Cay34041-25 25 mg -

6 - 10 Werktage*

418,00 €
Cay34041-50 50 mg -

6 - 10 Werktage*

779,00 €
 
Deslorelin is a peptide agonist of gonadotropin-releasing hormone (GnRH). It binds to the GnRH... mehr
Produktinformationen "Deslorelin (acetate)"
Deslorelin is a peptide agonist of gonadotropin-releasing hormone (GnRH). It binds to the GnRH receptor (GnRHR) with a Ki value of 0.1 nM. Deslorelin decreases testicular volume, semen volume, sperm motility, and total sperm count, as well as increases the percentage of abnormal sperm, in dogs when administered via a subcutaneous implant at doses of 3, 6, and 12 mg/kg. It decreases disease severity and plasma levels of estradiol, 17-hydroxyprogesterone, and androstenedione in ferrets with adrenocortical disease (ACD) when administered at doses ranging from 3 to 4.41 mg/kg per implant. Deslorelin (4.7 mg/implant per animal) suppresses ovulation and estrus in cats. Formulations containing deslorelin have been used in the management of ACD in ferrets and ovulation regulation and artificial insemination in horses.Formal Name: 6-D-tryptophan-9-(N-ethyl-L-prolinamide)-1-9-luteinizing hormone-releasing factor (swine), acetate. CAS Number: 1642579-30-3. Synonyms: D-Trp6-Pro9-des-Gly10-GnRH ethylamide, pGlu-His-Trp-Ser-Tyr-D-Trp-Leu-Arg-Pro-NHEt. Molecular Formula: C64H83N17O12 . XC2H4O2. Formula Weight: 1282.5. Purity: >98%. Formulation: A solid. Solubility: DMF: 5 mg/ml, DMSO: 5 mg/ml, Ethanol: 10 mg/ml. lambdamax: 219 nm. SMILES: OC(C=C1)=CC=C1C[C@H](NC([C@H](CO)NC([C@@H](NC([C@@H](NC([C@H]2NC(CC2)=O)=O)CC3=CN=CN3)=O)CC4=CNC5=CC=CC=C45)=O)=O)C(N[C@@H](C(N[C@@H](CC(C)C)C(N[C@@H](CCCNC(N)=N)C(N6[C@@H](CCC6)C(NCC)=O)=O)=O)=O)CC7=CNC8=CC=CC=C78)=O.CC(O)=O. InChi Code: InChI=1S/C64H83N17O12.C2H4O2/c1-4-68-62(92)53-16-10-24-81(53)63(93)46(15-9-23-69-64(65)66)74-56(86)47(25-35(2)3)75-58(88)49(27-37-30-70-43-13-7-5-11-41(37)43)77-57(87)48(26-36-17-19-40(83)20-18-36)76-61(91)52(33-82)80-59(89)50(28-38-31-71-44-14-8-6-12-42(38)44)78-60(90)51(29-39-32-67-34-72-39)79-55(85)45-21-22-54(84)73-45,1-2(3)4/h5-8,11-14,17-20,30-32,34-35,45-53,70-71,82-83H,4,9-10,15-16,21-29,33H2,1-3H3,(H,67,72)(H,68,92)(H,73,84)(H,74,86)(H,75,88)(H,76,91)(H,77,87)(H,78,90)(H,79,85)(H,80,89)(H4,65,66,69),1H3,(H,3,4)/t45-,46-,47-,48-,49+,50-,51-,52-,53-,/m0./s1. InChi Key: LYCYLGFSIXIXAB-NUZRHMIVSA-N.
Schlagworte: D-Trp6-Pro9-des-Gly10-GnRH ethylamide, pGlu-His-Trp-Ser-Tyr-D-Trp-Leu-Arg-Pro-NHEt, 6-D-tryptophan-9-(N-ethyl-L-prolinamide)-1-9-luteinizing hormone-releasing factor (swine), acetate
Hersteller: Cayman Chemical
Hersteller-Nr: 34041

Eigenschaften

Anwendung: GnRH peptide agonist
Konjugat: No
MW: 1282.5 D
Formel: C64H83N17O12 . XC2H4O2
Reinheit: >98%
Format: Solid

Datenbank Information

CAS : 1642579-30-3| Finde Alternativen
KEGG ID : K04280 | Finde Alternativen

Handhabung & Sicherheit

Lagerung: -20°C
Versand: +20°C (International: -20°C)
Signalwort: Danger
GHS-Piktogramme:
H-Sätze: H360
P-Sätze: P201, P202, P280, P308+313, P405, P501
Achtung
Nur für Forschungszwecke und Laboruntersuchungen: Nicht für die Anwendung im oder am Menschen!
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