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Artikelnummer: Cay35865-1
N-formyl-Nle-Leu-Phe-Nle-Tyr-Lys (fNLFNYK) is a synthetic chemotactic peptide. It binds to the formyl peptide receptor (FPR, Kd = 2.2 nM). fNLFNYK has been conjugated to various fluorophores to monitor FPR internalization.Formal Name: N-formyl-L-norleucyl-L-leucyl-L-phenylalanyl-L-norleucyl-L-tyrosyl-L-lysine,...
Schlagworte: | fNLFNYK, N-formyl-L-norleucyl-L-leucyl-L-phenylalanyl-L-norleucyl-L-tyrosyl-L-lysine, monotrifluoroacetate salt |
Anwendung: | Formyl peptide receptor (FPR1) binding, chemotactic peptide |
CAS | 2918767-97-0 |
MW: | 938.1 D |
ab 39,00 €
Artikelnummer: Cay35899-1
Atogepant is an antagonist of the calcitonin gene-related peptide (CGRP) receptor (IC50 = 0.026 nM). It is selective for the CGRP receptor over the adrenomedullin receptors (AM1) and AM2, calcitonin (CT) receptor, amylin receptor 1 (AMY1), and AMY3 receptor (IC50s = >18,000, 400, 6,274, 2.4 and 1,418 nM,...
Schlagworte: | (3'S)-1',2',5,7-tetrahydro-N-[(3S,5S,6R)-6-methyl-2-oxo-1-(2,2,2-trifluoroethyl)-5-(2,3,6-trifluorophenyl)-3-piperidinyl]-... |
Anwendung: | CGRP receptor (CALCRL) antagonist |
CAS | 1374248-81-3 |
MW: | 603.5 D |
409,00 €
Artikelnummer: Cay38850-10
KEMPFPKYPVEP Peptide is a peptide fragment of the dairy protein beta-casein. It can be produced by the protease M from A. oryzae and is found in dairy products fermented by fungi but not bacteria. KEMPFPKYPVEP Peptide (2 mg/kg) increases the levels of dopamine, norepinephrine, and homovanillic acid, but not...
Schlagworte: | L-lysyl-L-alpha-glutamyl-L-methionyl-L-prolyl-L-phenylalanyl-L-prolyl-L-lysyl-L-tyrosyl-L-prolyl-L-valyl-L-alpha-glutamyl-... |
Anwendung: | Beta-casein peptide fragment |
MW: | 1461.7 D |
ab 34,00 €
Artikelnummer: Cay39723-1
Bradykinin (2-9) is a metabolite of the endogenous vasodilator peptide bradykinin (Cay-37408). It is formed from bradykinin via N-terminal cleavage by carboxypeptidase.Synonyms: BK (2-9), (Des-Arg1)-BK, (Des-Arg1)-Bradykinin, H-Pro-Pro-Gly-Phe-Ser-Pro-Phe-Arg-OH. Molecular Formula: C44H61N11O10 . XCF3COOH. Formula...
Schlagworte: | (Des-Arg1)-BK, (Des-Arg1)-Bradykinin, BK (2-9), H-Pro-Pro-Gly-Phe-Ser-Pro-Phe-Arg-OH, (Des-Arg1)-BDK |
Anwendung: | Bradykinin metabolite |
MW: | 904 D |
ab 61,00 €
Artikelnummer: Cay39725-1
Heparin-binding peptide is a synthetic peptide fragment corresponding to residues 1,892-1,899 of the C-terminal heparin-binding domain of fibronectin. It induces focal adhesion formation in pre-spread human embryonic fibroblasts (HEFs) when used at concentrations ranging from 1 to 1,000 µg/ml. Heparin-binding...
Schlagworte: | Fibronectin Adhesion-promoting Peptide, Fibronectin Peptide V, FN-C/H-V,... |
Anwendung: | Fibronectin peptide fragment |
MW: | 1023.2 D |
ab 34,00 €
Artikelnummer: Cay39727-1
Kassinin is a tachykinin neuropeptide and agonist of the neurokinin-2 (NK2) and NK3 receptors. It is selective for the NK2 and NK3 receptors over the NK1 receptor. Kassinin (1 µM) increases the short-circuit current in isolated frog skin. It induces contractions in isolated guinea pig ileum and isolated rabbit...
Anwendung: | Tachykinin neuropeptide |
MW: | 1334.6 D |
ab 88,00 €
Artikelnummer: Cay39728-1
Buccalin A is a neuropeptide that is found in gastropod motor neurons and is involved in neuromuscular signaling. It reduces current-induced muscle contraction amplitude but not muscle relaxation rate in isolated and washed A. californica accessory radula closer (ARC) muscle fibers when used at a concentration of 10...
Schlagworte: | (3S,6S,9S,12S,15S,18S,27S)-3-((S)-2-(2-aminoacetamido)-4-(methylthio)butanamido)-15-benzyl-27-carbamoyl-6,18-bis(hydroxyme... |
Anwendung: | Neuropeptide |
MW: | 1053.2 D |
ab 39,00 €
Artikelnummer: Cay40142-1
PF-05190457 is an inverse agonist of the growth hormone secretagogue receptor (GHS-R), which is also known as the ghrelin receptor. It selectively binds to GHS-R (Ki = 4.37 nM) over M2 muscarinic acetylcholine receptors (mAChRs, Ki = 1,950 nM) and the serotonin (5-HT) receptor subtype 5-HT2B (IC50 = 3,700 nM)....
Schlagworte: | 1-[2-[(1R)-2,3-dihydro-5-(6-methyl-4-pyrimidinyl)-1H-inden-1-yl]-2,7-diazaspiro[3.5]non-7-yl]-2-(2-methylimidazo[2,1-b]thi... |
Anwendung: | GHS-R inverse agonist |
CAS | 1334782-79-4 |
MW: | 512.7 D |
ab 47,00 €
Artikelnummer: Cay40151-1
Myomodulin A is a gastropod neuropeptide. It is found in gastropod ventral lobe neurons, neural elements of the accessory radula closer (ARC) muscle, and penis nerve. Myomodulin A is biosynthesized by ARC motor neurons in A. californica and potentiates motor neuron-elicited contractions of the A. californica buccal...
Schlagworte: | MMa, MYOMOD1, Pro-Met-Ser-Met-Leu-Arg-Leu-NH2, L-prolyl-L-methionyl-L-seryl-L-methionyl-L-leucyl-L-arginyl-L-leucinamide,... |
Anwendung: | Gastropod neuropeptide |
MW: | 846.1 D |
ab 34,00 €
Artikelnummer: Cay40170-10
Semaglutide is an agonist of glucagon-like peptide 1 receptor (GLP-1R, EC50 = 6.2 pM in a reporter assay using BHK cells expressing the human receptor). It decreases blood glucose levels in the db/db mouse model of type 2 diabetes (ED50 = 98%. Formulation: (Request formulation change), A solid. Solubility:...
Schlagworte: | L-histidyl-2-methylalanyl-L-alpha-glutamylglycyl-L-threonyl-L-phenylalanyl-L-threonyl-L-seryl-L-alpha-aspartyl-L-valyl-L-s... |
Anwendung: | GLP-1R agonist |
CAS | 2924330-56-1 |
MW: | 4113.6 D |
ab 117,00 €
Artikelnummer: Cay40231-1
Semaglutide is an agonist of glucagon-like peptide 1 receptor (GLP-1R, EC50 = 6.2 pM in a reporter assay using BHK cells expressing the human receptor). It decreases blood glucose levels in the db/db mouse model of type 2 diabetes (ED50 = 98%. Formulation: (Request formulation change), A solid. Solubility: Methanol:...
Anwendung: | GLP-1R agonist |
CAS | 910463-68-2 |
MW: | 4113.6 D |
ab 34,00 €
Artikelnummer: NZY-VP0003
Diapause-specific venom peptide is a recombinant peptide purified from Escherichia coli that was originally isolated from the venom of Gastrophysa atrocyanea (leaf beetle). The endogenous diapausespecific peptide has attractive properties, such as antifungal activity, N-type voltage-gated Ca 2+ channel blocker and...
Anwendung: | Drug discovery |
MW: | 44,7 kD |
449,00 €