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NEU
Artikelnummer: Cay40170-10
Semaglutide is an agonist of glucagon-like peptide 1 receptor (GLP-1R, EC50 = 6.2 pM in a reporter assay using BHK cells expressing the human receptor). It decreases blood glucose levels in the db/db mouse model of type 2 diabetes (ED50 = 98%. Formulation: (Request formulation change), A solid. Solubility:...
Schlagworte: | L-histidyl-2-methylalanyl-L-alpha-glutamylglycyl-L-threonyl-L-phenylalanyl-L-threonyl-L-seryl-L-alpha-aspartyl-L-valyl-L-s... |
Anwendung: | GLP-1R agonist |
CAS | 2924330-56-1 |
MW: | 4113.6 D |
ab 117,00 €
NEU
Artikelnummer: Cay40231-1
Semaglutide is an agonist of glucagon-like peptide 1 receptor (GLP-1R, EC50 = 6.2 pM in a reporter assay using BHK cells expressing the human receptor). It decreases blood glucose levels in the db/db mouse model of type 2 diabetes (ED50 = 98%. Formulation: (Request formulation change), A solid. Solubility: Methanol:...
Anwendung: | GLP-1R agonist |
CAS | 910463-68-2 |
MW: | 4113.6 D |
ab 34,00 €
Artikelnummer: Cay36912-1
Exendin-4 (3-39) amide is an agonist of glucagon-like peptide 1 receptor (GLP-1R) and an active metabolite of exendin-4 (48-86) amide (Cay-11096). It is formed from exendin-4 (48-86) amide in rat liver homogenates. Exendin-4 (3-39) amide induces cAMP accumulation in HEK293 cells expressing human GLP-1R (EC50 = 9...
Schlagworte: | Exendin (3-39),... |
Anwendung: | GLP-1R agonist, active exendin-4 (48-86) amide metabolite |
MW: | 3992.4 D |
ab 47,00 €
Artikelnummer: Cay36922-1
Fz7-21 is a peptide antagonist of the frizzled family G protein-coupled receptor 7 (FZD7, IC50 = 100 nM). It inhibits Wnt3a-induced beta-catenin signaling in a reporter assay using HEK293 cells. Fz7-21 (100 µM) reduces the number of cells positive for leucine-rich alpha-2-glycoprotein 5 (Lrg5), a marker of...
Schlagworte: | dFz7-21,... |
Anwendung: | FZD7 receptor peptide antagonist |
MW: | 1796 D |
ab 34,00 €
Artikelnummer: Cay36962-1
F9170 is an antiviral peptide corresponding to amino acids 789-803 of the HIV-1 envelope glycoprotein. It binds to the LLP1 domain within the HIV-1 envelope protein cytoplasmic tail and inhibits HIV-1 IIIB infection of MT-2 cells (EC50 = 0.19 µM). F9170 (3 mg/kg) reduces plasma viral load in a rhesus macaque model...
Schlagworte: | lycyl-L-tryptophyl-L-alpha-glutamyl-L-alanyl-L-leucyl-L-lysyl-L-tyrosyl-L-leucyl-L-tryptophyl-L-asparaginyl-L-leucyl-L-leu... |
Anwendung: | Antiviral peptide |
MW: | 1983.3 D |
ab 39,00 €
Artikelnummer: Cay37495-1
Wasabi receptor toxin (WaTx) (36-68) is a cell-penetrating peptide that corresponds to the mature toxin sequence and is an activator of transient receptor potential ankyrin 1 (TRPA1). It selectively induces currents in HEK293T cells expressing human TRPA1 (EC50 = 15 nM) over cells expressing human TRP melastatin 8...
Schlagworte: | Wasabi Receptor Toxin (36-68),... |
Anwendung: | Cell-penetrating peptide, TRPA1 activator |
MW: | 3855.3 D |
ab 93,00 €
Artikelnummer: Cay37501-1
Tat-ASIC1a (1-20) is a synthetic peptide composed of the cell-penetrating peptide sequence from the HIV-1 Tat protein transduction domain linked to a 20-amino acid peptide corresponding to amino acids 1-20 of acid-sensing ion channel 1a (ASIC1a). It prevents acid-induced association of ASIC1a with...
Schlagworte: | NT1-20, Tat-Acid-sensing Ion Channel 1a (1-20) |
Anwendung: | Peptide, ASIC1a-RIPK1 association blocker |
MW: | 3655.2 D |
ab 80,00 €
Artikelnummer: Cay37507-1
Fyn peptide (410-430) is a peptide fragment of the Src family non-receptor tyrosine kinase Fyn containing Tyr420, which undergoes autophosphorylation upon activation of full-length Fyn. Formal name:...
Schlagworte: | Src (408-428) (mouse), Src (409-429) (human, rat),... |
Anwendung: | Fyn peptide fragment |
MW: | 2362.7 D |
ab 34,00 €
Artikelnummer: Cay37715-1
Aspartyl-alanyl-diketopiperazine is an immunosuppressive diketopiperazine derivative of a human serum albumin (HSA) peptide. It reduces antigen-induced TNF-alpha and IFN-gamma production in isolated human T cells when used at a concentration of 500 µM. Formal name: 5S-methyl-3,6-dioxo-2S-piperazineacetic acid. CAS...
Schlagworte: | DA-DKP, 5S-methyl-3,6-dioxo-2S-piperazineacetic acid |
Anwendung: | Immunosuppressive diketopiperazine HSA peptide derivative |
CAS | 110954-19-3 |
MW: | 186.2 D |
ab 57,00 €
Artikelnummer: Cay38165-1
SAP15 is a cell-penetrating peptide consisting of the C-terminal amino acids 52-67 of human beta-defensin-3 (Cay-24578). Formal name: glycyl-L-lysyl-L-cysteinyl-L-seryl-L-threonyl-L-arginylglycyl-L-arginyl-L-lysyl-L-cysteinyl-L-cysteinyl-L-arginyl-L-arginyl-L-lysyl-L-lysine, trifluoroacetate salt. Synonyms:...
Schlagworte: | Synthetic Anti-inflammatory Peptide 15,... |
Anwendung: | Cell-penetrating peptide |
MW: | 1767.2 D |
ab 47,00 €
Artikelnummer: Cay38759-10
Fmoc-Thr(GalNAc(Ac)3-alpha-D)-OH is a building block. It has been used in the synthesis of antibacterial glycopeptides and anticancer glycopeptide vaccines. Formal name: N-[(9H-fluoren-9-ylmethoxy)carbonyl]-O-[3,4,6-tri-O-acetyl-2-(acetylamino)-2-deoxy-alpha-D-galactopyranosyl]-L-threonine. CAS Number: 116783-35-8....
Schlagworte: | N-[(9H-fluoren-9-ylmethoxy)carbonyl]-O-[3,4,6-tri-O-acetyl-2-(acetylamino)-2-deoxy-alpha-D-galactopyranosyl]-L-threonine |
Anwendung: | Building block, glycopeptide synthesis |
CAS | 116783-35-8 |
MW: | 670.7 D |
ab 114,00 €
Artikelnummer: Cay38773-1
GR94800 is a synthetic peptide neurokinin-2 (NK2) receptor antagonist (Ki = 1 nM). It is selective for NK2 over NK3 (Ki = 1,000 nM). GR94800 (0.1 and 1 µM) decreases balloon distension-induced submaximal and maximal atropine-resistant ascending excitatory reflex (AER) in isolated guinea pig ileum circular muscles....
Schlagworte: | Benzoyl-Ala-Ala-trp-Phe-pro-Pro-Nle-NH2, GR98400,... |
Anwendung: | NK2 receptor (tachykinin receptor 2, TACR2) antagonist, synthetic peptide |
CAS | 141636-65-9 |
MW: | 904.1 D |
ab 39,00 €