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Artikelnummer: Cay39727-1
Kassinin is a tachykinin neuropeptide and agonist of the neurokinin-2 (NK2) and NK3 receptors. It is selective for the NK2 and NK3 receptors over the NK1 receptor. Kassinin (1 µM) increases the short-circuit current in isolated frog skin. It induces contractions in isolated guinea pig ileum and isolated rabbit...
Anwendung: | Tachykinin neuropeptide |
MW: | 1334.6 D |
ab 88,00 €
Artikelnummer: Cay39728-1
Buccalin A is a neuropeptide that is found in gastropod motor neurons and is involved in neuromuscular signaling. It reduces current-induced muscle contraction amplitude but not muscle relaxation rate in isolated and washed A. californica accessory radula closer (ARC) muscle fibers when used at a concentration of 10...
Schlagworte: | (3S,6S,9S,12S,15S,18S,27S)-3-((S)-2-(2-aminoacetamido)-4-(methylthio)butanamido)-15-benzyl-27-carbamoyl-6,18-bis(hydroxyme... |
Anwendung: | Neuropeptide |
MW: | 1053.2 D |
ab 39,00 €
Artikelnummer: Cay40142-1
PF-05190457 is an inverse agonist of the growth hormone secretagogue receptor (GHS-R), which is also known as the ghrelin receptor. It selectively binds to GHS-R (Ki = 4.37 nM) over M2 muscarinic acetylcholine receptors (mAChRs, Ki = 1,950 nM) and the serotonin (5-HT) receptor subtype 5-HT2B (IC50 = 3,700 nM)....
Schlagworte: | 1-[2-[(1R)-2,3-dihydro-5-(6-methyl-4-pyrimidinyl)-1H-inden-1-yl]-2,7-diazaspiro[3.5]non-7-yl]-2-(2-methylimidazo[2,1-b]thi... |
Anwendung: | GHS-R inverse agonist |
CAS | 1334782-79-4 |
MW: | 512.7 D |
ab 47,00 €
Artikelnummer: Cay40151-1
Myomodulin A is a gastropod neuropeptide. It is found in gastropod ventral lobe neurons, neural elements of the accessory radula closer (ARC) muscle, and penis nerve. Myomodulin A is biosynthesized by ARC motor neurons in A. californica and potentiates motor neuron-elicited contractions of the A. californica buccal...
Schlagworte: | MMa, MYOMOD1, Pro-Met-Ser-Met-Leu-Arg-Leu-NH2, L-prolyl-L-methionyl-L-seryl-L-methionyl-L-leucyl-L-arginyl-L-leucinamide,... |
Anwendung: | Gastropod neuropeptide |
MW: | 846.1 D |
ab 34,00 €
Artikelnummer: Cay40170-10
Semaglutide is an agonist of glucagon-like peptide 1 receptor (GLP-1R, EC50 = 6.2 pM in a reporter assay using BHK cells expressing the human receptor). It decreases blood glucose levels in the db/db mouse model of type 2 diabetes (ED50 = 98%. Formulation: (Request formulation change), A solid. Solubility:...
Schlagworte: | L-histidyl-2-methylalanyl-L-alpha-glutamylglycyl-L-threonyl-L-phenylalanyl-L-threonyl-L-seryl-L-alpha-aspartyl-L-valyl-L-s... |
Anwendung: | GLP-1R agonist |
CAS | 2924330-56-1 |
MW: | 4113.6 D |
ab 117,00 €
Artikelnummer: Cay40231-1
Semaglutide is an agonist of glucagon-like peptide 1 receptor (GLP-1R, EC50 = 6.2 pM in a reporter assay using BHK cells expressing the human receptor). It decreases blood glucose levels in the db/db mouse model of type 2 diabetes (ED50 = 98%. Formulation: (Request formulation change), A solid. Solubility: Methanol:...
Anwendung: | GLP-1R agonist |
CAS | 910463-68-2 |
MW: | 4113.6 D |
ab 34,00 €
Artikelnummer: NZY-VP0003
Diapause-specific venom peptide is a recombinant peptide purified from Escherichia coli that was originally isolated from the venom of Gastrophysa atrocyanea (leaf beetle). The endogenous diapausespecific peptide has attractive properties, such as antifungal activity, N-type voltage-gated Ca 2+ channel blocker and...
Anwendung: | Drug discovery |
MW: | 44,7 kD |
449,00 €
Artikelnummer: NZY-VP0006
Alpha-like toxin Bom4 venom peptide is a recombinant peptide purified from Escherichia coli that was originally isolated from the venom of Buthus occitanus mardochei (Moroccan scorpion). Bom4 toxin binds voltage-independently sodium channels (Nav) and inhibits sodium channels inactivation, thereby blocking neuronal...
Anwendung: | Drug discovery |
MW: | 72,96 kD |
449,00 €
Artikelnummer: NZY-VP0007
Insecticidal LalT1 venom peptide is a recombinant peptide purified from Escherichia coli that was originally isolated from the venom of Liocheles australasiae (Dwarf wood scorpion). The endogenous Insecticidal LalT1 peptide affects the activity of both ryanodinesensitive calcium-release channels RyR1 and RyR2. This...
Anwendung: | Drug discovery |
MW: | 42,07 kD |
449,00 €
Artikelnummer: NZY-VP0009
Potassium channel toxin Aek venom peptide is a recombinant peptide purified from Escherichia coli that was originally isolated from the venom of sea anemone Actinia equina (Beadlet anemone). Aek toxin binds to voltage-dependent potassium channels (Kv1/KCNA), thereby inhibiting the binding of 125I-alphadendrotoxin to...
Anwendung: | Drug discovery |
MW: | 38,13 kD |
449,00 €
Artikelnummer: NZY-VP0010
Delta-stichotoxin-Hcr1a (Neurotoxin 3) venom peptide is a recombinant peptide purified from Escherichia coli that was originally isolated from the venom of Heteractis crispa (Leathery sea anemone). This venom peptide binds to voltage-gated sodium channels (Nav), delaying their inactivation during signal...
Anwendung: | Drug discovery |
MW: | 53,86 kD |
449,00 €
Artikelnummer: NZY-VP0013
Short neurotoxin 2 venom peptide is a recombinant peptide purified from Escherichia coli that was originally isolated from the venom of Naja annulifera. This venom peptide binds to muscle nicotinic acetylcholine receptor (nAChR) and inhibits the acetylcholine ligation to receptor, blocking the neuronal transmission....
Anwendung: | Drug discovery |
MW: | 69,15 kD |
449,00 €