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NEU
![[Ala1,3,11,15]-Endothelin-1 (trifluoroacetate salt)](https://www.biomol.com/media/image/ca/29/2a/Cay39017-1_200x200.png "[Ala1,3,11,15]-Endothelin-1 (trifluoroacetate salt)")
[Ala1,3,11,15]-Endothelin-1 (trifluoroacetate salt)
Artikelnummer: Cay39017-1
[Ala1,3,11,15]-Endothelin-1 is an endothelin receptor type B (ETB) agonist and linear synthetic peptide derivative of endothelin-1 in which all four cysteine residues have been substituted with alanine. It selectively binds to ETB over ETA receptors (IC50s = 0.33 and 570 nM, respectively, for the porcine receptors)....
| Schlagworte: | [Ala1,3,11,15]-ET-1, 4-Ala-ET-1,... |
| Anwendung: | ETB receptor agonist |
| MW: | 2367.7 D |
ab 53,00 €
NEU
Aureobasidin A
Artikelnummer: Cay39722-10
Aureobasidin A is a cyclic depsipeptide that has been found in A. pullulans and has diverse biological activities. It inhibits inositol phosphorylceramide synthase, an enzyme involved in sphingolipid biosynthesis (Kis = 0.18 and 0.23 for the C. albicans and S. cerevisiae enzymes, respectively). Aureobasidin A also...
| Schlagworte: | Antibiotic R 106I, Basifungin, LY295337, NK 204, R 106-1,... |
| Anwendung: | Bioactive cyclic depsipeptide |
| CAS | 127785-64-2 |
| MW: | 1101.4 D |
ab 218,00 €
NEU
Retatrutide (sodium salt)
Artikelnummer: Cay39747-1
Retatrutide is a triple agonist of the glucagon receptor (GCGR), glucagon-like peptide 1 receptor (GLP-1R), and gastric inhibitory polypeptide receptor (GIP receptor), also known as the glucose-dependent insulinotropic polypeptide receptor. It induces cAMP accumulation in HEK293 cells expressing the human GCGR,...
| Schlagworte: | LY3437943,... |
| Anwendung: | GCGR / GLP-1R / GIPR triple agonist |
| MW: | 4731.3 D |
ab 77,00 €
NEU
PE 22-28 (acetate)
Artikelnummer: Cay39986-1
PE 22-28 is a peptide inhibitor of the two-pore domain potassium channel K2P2.1/TREK1 (IC50 = 0.1 nM in HEK293 cells expressing the human channel) and a fragment of spadin (Cay-36762). It is selective for K2P2.1/TREK1 over K2P10.1 /TREK2, K2P13.1/TRAAK, K2P18.1/TRESK, and K2P3.1/TASK1 in HEK293 cells expressing the...
| Schlagworte: | Gly-Val-Ser-Trp-Gly-Leu-Arg-OH, glycyl-L-valyl-L-seryl-L-tryptophylglycyl-L-leucyl-L-arginine, acetate |
| Anwendung: | K2P2.1/TREK1 peptide inhibitor |
| MW: | 773.9 D |
ab 119,00 €
NEU
![[Asp371]-Tyrosinase (369-377) (human) (trifluoroacetate salt)](https://www.biomol.com/media/image/b8/fa/ce/Cay40152-1_200x200.png "[Asp371]-Tyrosinase (369-377) (human) (trifluoroacetate salt)")
[Asp371]-Tyrosinase (369-377) (human) (trifluoroacetate...
Artikelnummer: Cay40152-1
[Asp371]-Tyrosinase (369-377) is a naturally occurring tyrosinase antigen peptide. It is formed via post-translational modification of Asn371. [Asp371]-Tyrosinase (369-377) binds to MHC class I subtype HLA-A*0201-positive T2 cells (IC50 = 1.2 µg/ml) and induces lysis of HLA-A2.1-positive T2 cells incubated with...
| Schlagworte: | [Asp370]-Tyrosinase (368-376), Tyr-Met-Asp-Gly-Thr-Met-Ser-Gln-Val,... |
| Anwendung: | Tyrosinase antigen peptide |
| MW: | 1031.2 D |
ab 34,00 €
NEU
Strep-tag(R)II peptide
Artikelnummer: IBA-2-1018-002
Synthetic Strep-tag(R)II peptide recognized by Strep-Tactin(R), Strep-Tactin(R)XT as well as the monoclonal antibodies, StrepMAB-Classic and StrepMAB-Immo. It can be used for competitive elution of Strep-tag(R)II fusion proteins or as control protein in dot blot assays.
| Anwendung: | Synthetic peptide recognized by Strep-Tactin(R) / Strep-Tactin(R)XT |
100,00 €
N-formyl-Nle-Leu-Phe-Nle-Tyr-Lys (trifluoroacetate salt)
Artikelnummer: Cay35865-1
N-formyl-Nle-Leu-Phe-Nle-Tyr-Lys (fNLFNYK) is a synthetic chemotactic peptide. It binds to the formyl peptide receptor (FPR, Kd = 2.2 nM). fNLFNYK has been conjugated to various fluorophores to monitor FPR internalization.Formal Name: N-formyl-L-norleucyl-L-leucyl-L-phenylalanyl-L-norleucyl-L-tyrosyl-L-lysine,...
| Schlagworte: | fNLFNYK, N-formyl-L-norleucyl-L-leucyl-L-phenylalanyl-L-norleucyl-L-tyrosyl-L-lysine, monotrifluoroacetate salt |
| Anwendung: | Formyl peptide receptor (FPR1) binding, chemotactic peptide |
| CAS | 2918767-97-0 |
| MW: | 938.1 D |
ab 39,00 €
Atogepant
Artikelnummer: Cay35899-1
Atogepant is an antagonist of the calcitonin gene-related peptide (CGRP) receptor (IC50 = 0.026 nM). It is selective for the CGRP receptor over the adrenomedullin receptors (AM1) and AM2, calcitonin (CT) receptor, amylin receptor 1 (AMY1), and AMY3 receptor (IC50s = >18,000, 400, 6,274, 2.4 and 1,418 nM,...
| Schlagworte: | (3'S)-1',2',5,7-tetrahydro-N-[(3S,5S,6R)-6-methyl-2-oxo-1-(2,2,2-trifluoroethyl)-5-(2,3,6-trifluorophenyl)-3-piperidinyl]-... |
| Anwendung: | CGRP receptor (CALCRL) antagonist |
| CAS | 1374248-81-3 |
| MW: | 603.5 D |
409,00 €
KEMPFPKYPVEP Peptide (bovine, ovine) (trifluoroacetate salt)
Artikelnummer: Cay38850-10
KEMPFPKYPVEP Peptide is a peptide fragment of the dairy protein beta-casein. It can be produced by the protease M from A. oryzae and is found in dairy products fermented by fungi but not bacteria. KEMPFPKYPVEP Peptide (2 mg/kg) increases the levels of dopamine, norepinephrine, and homovanillic acid, but not...
| Schlagworte: | L-lysyl-L-alpha-glutamyl-L-methionyl-L-prolyl-L-phenylalanyl-L-prolyl-L-lysyl-L-tyrosyl-L-prolyl-L-valyl-L-alpha-glutamyl-... |
| Anwendung: | Beta-casein peptide fragment |
| MW: | 1461.7 D |
ab 34,00 €
Bradykinin (2-9) (trifluoroacetate salt)
Artikelnummer: Cay39723-1
Bradykinin (2-9) is a metabolite of the endogenous vasodilator peptide bradykinin (Cay-37408). It is formed from bradykinin via N-terminal cleavage by carboxypeptidase.Synonyms: BK (2-9), (Des-Arg1)-BK, (Des-Arg1)-Bradykinin, H-Pro-Pro-Gly-Phe-Ser-Pro-Phe-Arg-OH. Molecular Formula: C44H61N11O10 . XCF3COOH. Formula...
| Schlagworte: | (Des-Arg1)-BK, (Des-Arg1)-Bradykinin, BK (2-9), H-Pro-Pro-Gly-Phe-Ser-Pro-Phe-Arg-OH, (Des-Arg1)-BDK |
| Anwendung: | Bradykinin metabolite |
| MW: | 904 D |
ab 61,00 €
Heparin-binding Peptide (trifluoroacetate salt)
Artikelnummer: Cay39725-1
Heparin-binding peptide is a synthetic peptide fragment corresponding to residues 1,892-1,899 of the C-terminal heparin-binding domain of fibronectin. It induces focal adhesion formation in pre-spread human embryonic fibroblasts (HEFs) when used at concentrations ranging from 1 to 1,000 µg/ml. Heparin-binding...
| Schlagworte: | Fibronectin Adhesion-promoting Peptide, Fibronectin Peptide V, FN-C/H-V,... |
| Anwendung: | Fibronectin peptide fragment |
| MW: | 1023.2 D |
ab 34,00 €
Kassinin (frog) (trifluoroacetate salt)
Artikelnummer: Cay39727-1
Kassinin is a tachykinin neuropeptide and agonist of the neurokinin-2 (NK2) and NK3 receptors. It is selective for the NK2 and NK3 receptors over the NK1 receptor. Kassinin (1 µM) increases the short-circuit current in isolated frog skin. It induces contractions in isolated guinea pig ileum and isolated rabbit...
| Anwendung: | Tachykinin neuropeptide |
| MW: | 1334.6 D |
ab 88,00 €