Uridine 5'-diphosphogalactose disodium salt

Uridine 5'-diphospho-alpha-D-galactose (UDP-Gal) is a nucleotide sugar. UDP-Gal is a donor substrate for galactosyltransferases used in the biosynthesis of galactose-containing oligosaccharides. UDP-Gal has been used as a component in galactosyltransferase labeling buffer to prelabel terminal N-acetylglucosamine (GlcNAc) on immunoglobulin chains. It has also been used as a component in Hyp O-galactosyltransferase (HPGT) assay. Decreased red blood cell levels of UDP-Gal are found in patients with maple syrup urine disease or phenylketonuria. Product References: (1) J.B. Gibson, et al., Am. J. Clin. Nutr. 63, 704 (1996) , (2) N. Miura, et al., J. Biochem. 120, 236 (1996) , (3) C.L. Stults, et al., Glycobiol. 9, 661 (1999) , (4) Y. Zou, et al., Carbohydr. Res. 373, 76 (2013) Appearance: White to off-white powder. Solubility: Soluble in water (50mg/ml). Identity: Determined by 1H-NMR. InChi Key: VIKIOTCWAGIIJZ-QKYKBPIOSA-M Smiles: O[C@H]1[C@@H](O)[C@H](N2C(NC(C=C2)=O)=O)O[C@@H]1COP([O-])(OP([O])(O[C@H]3O[C@H](CO)[C@H](O)[C@H](O)[C@H]3O)=O)=O.[Na].[Na+]