PtdIns-(4,5)-P2 (1,2-dipamitoyl)-d62 (sodium salt)

PtdIns-(4,5)-P2 (1,2-dipamitoyl)-d62 (sodium salt)
Artikelnummer Größe Datenblatt Manual SDB Lieferzeit Menge Preis
Cay10005615-25 25 µg -

5 - 10 Werktage*

94,00 €
Cay10005615-50 50 µg -

5 - 10 Werktage*

179,00 €
Cay10005615-100 100 µg -

5 - 10 Werktage*

338,00 €
 
PtdIns-(4,5)-P2 (1,2-dipalmitoyl)-d62 (sodium salt) contains 62 deuterium atoms at the 2, 2', 3,... mehr
Produktinformationen "PtdIns-(4,5)-P2 (1,2-dipamitoyl)-d62 (sodium salt)"
PtdIns-(4,5)-P2 (1,2-dipalmitoyl)-d62 (sodium salt) contains 62 deuterium atoms at the 2, 2', 3, 3', 4, 4', 5, 5', 6, 6', 7, 7', 8, 8', 9, 9', 10, 10', 11, 11', 12, 12', 13, 13', 14, 14', 15, 15', 16, 16, and 16 positions of each fatty acyl chain. It is intended for use as an internal standard for the quantification of PtdIns-(4,5)-P2 (1,2-dipalmitoyl) (sodium salt) by GC- or LC-mass spectrometry. The phosphatidylinositol (PtdIns) phosphates represent a small percentage of total membrane phospholipids. However, they play a critical role in the generation and transmission of cellular signals. PtdIns-4,5-P2-(1,2-dipalmitoyl)-d62 is a synthetic analog of natural PtdIns containing deuterated C16:0 fatty acids at the sn-1 and sn-2 positions. This synthetic standard features the same inositol and diacyl glycerol (DAG) stereochemistry as that of the natural compound. The natural compound is the product of phosphatidylinositol 4-phosphate 5-kinase acting on PtdIns-(4)-P1. Hydrolysis of PtdIns-(4,5)-P2 by phosphoinositide (PI)-specific phospholipase C generates inositol triphosphate (IP3) and DAG which are key second messengers in an intricate biochemical signal transduction cascade. Formal Name: 1-(1,2-dihexadecanoyl(2,2',3,3',4,4',5,5',6,6',7,7',8,8',9,9',10,10',11,11',12,12',13,13',14,14',15,16,16,16-d31)phosphatidyl)inositol-4,5-bisphosphate, trisodium salt. Synonyms: DPPI-4,5-P2-d62, Phosphatidylinositol-4,5-diphosphate C16-d62. Molecular Formula: C41H16D62O19P3 . 3Na. Formula Weight: 1099.3. Purity: >99% deuterated forms (d1-d62). Formulation: A lyophilized powder. SMILES: O[C@@H]1[C@@H](OP([O-])(O)=O)[C@H](OP([O-])(O)=O)[C@@H](O)[C@@H](O)[C@H]1OP([O-])(OCC(COC(C([2H])([2H])C([2H])([2H])C([2H])([2H])C([2H])([2H])C([2H])([2H])C([2H])([2H])C([2H])([2H])C([2H])([2H])C([2H])([2H])C([2H])([2H])C([2H])([2H])C([2H])([2H])C([2. InChi Code: InChI=1S/C41H81O19P3/c1-3-5-7-9-11-13-15-17-19-21-23-25-27-29-34(42)55-31-33(57-35(43)30-28-26-24-22-20-18-16-14-12-10-8-6-4-2)32-56-63(53,54)60-39-36(44)37(45)40(58-61(47,48)49)41(38(39)46)59-62(50,51)52/h33,36-41,44-46H,3-32H2,1-2H3,(H,53,54)(H2,47. InChi Key: HKWJHKSHEWVOSS-ZOXFJUOSSA-K. Side Chain Carbon Sum: 32:0.
Schlagworte: DPPI-4,5-P2-d62, Phosphatidylinositol-4,5-diphosphate C16-d62, 1-(1,2-dihexadecanoyl(2,2',3,3',4,4',5,5',6,6',7,7',8,8',9,9',10,10',11,11',12,12',13,13',14,14',15,16,16,16-d31)phosphatidyl)inositol-4,5-bisphosphate, trisodium salt
Hersteller: Cayman Chemical
Hersteller-Nr: 10005615

Eigenschaften

Anwendung: Standard
MW: 1099.3 D
Formel: C41H16D62O19P3 . 3Na
Reinheit: >99% deuterated forms (d1-d62)
Format: Solid

Datenbank Information

Handhabung & Sicherheit

Lagerung: -20°C
Versand: -20°C (International: -20°C)
Achtung
Nur für Forschungszwecke und Laboruntersuchungen: Nicht für die Anwendung im oder am Menschen!
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