PtdIns-(3,4)-P2 (1,2-dihexanoyl) (sodium salt)

The phosphatidylinositol (PtdIns) phosphates represent a small percentage of total membrane phospholipids. However, they play a critical role in the generation and transmission of cellular signals. PtdIns-(3,4)-P2 (1,2-dihexanoyl) is a synthetic analog of natural phosphatidylinositol (PtdIns) featuring C6:0 fatty acids at the sn-1 and sn-2 positions. The compound features the same inositol and diacylglycerol (DAG) stereochemistry as that of the natural compound. The natural compound is the product of phosphorylation-dephosphorylation involving PtdIns-3-kinase and 5-phosphatases. The 3D-phosphorylated PtdIns are resistant to hydrolysis by phospholipase C. Formal Name: 1-(1,2-dihexanoylphosphatidyl)inositol-3,4-bisphosphate, trisodium salt. Synonyms: DHPI-3,4-P2, Phosphatidylinositol-3,4-bisphosphate C-6. Molecular Formula: C21H38O19P3 . 3Na. Formula Weight: 756.4. Purity: >98%. Formulation: A lyophilized powder. SMILES: CCCCCC(OC[C@H](COP(O[C@@H]1[C@H](O)[C@H](OP([O-])(O)=O)[C@@H](OP([O-])(O)=O)[C@H](O)[C@H]1O)([O-])=O)OC(CCCCC)=O)=O.[Na+].[Na+].[Na+]. InChi Code: InChI=1S/C21H41O19P3.3Na/c1-3-5-7-9-14(22)35-11-13(37-15(23)10-8-6-4-2)12-36-43(33,34)40-19-16(24)17(25)20(38-41(27,28)29)21(18(19)26)39-42(30,31)32,,,/h13,16-21,24-26H,3-12H2,1-2H3,(H,33,34)(H2,27,28,29)(H2,30,31,32),,,/q,3*+1/p-3/t13-,16-,17-,18+,1. InChi Key: RLSRPPXCLVFTHW-LSGXMVLJSA-K. Side Chain Carbon Sum: 12:0.