Prostaglandin D2

Prostaglandin D2
Artikelnummer Größe Datenblatt Manual SDB Lieferzeit Menge Preis
Cay12010-1 1 mg -

5 - 10 Werktage*

49,00 €
Cay12010-5 5 mg -

5 - 10 Werktage*

220,00 €
Cay12010-10 10 mg -

5 - 10 Werktage*

367,00 €
Cay12010-25 25 mg -

5 - 10 Werktage*

793,00 €
 
Prostaglandin D2 (PGD2) is the major eicosanoid product of mast cells and is released in large... mehr
Produktinformationen "Prostaglandin D2"
Prostaglandin D2 (PGD2) is the major eicosanoid product of mast cells and is released in large quantities during allergic and asthmatic anaphylaxis. Mastocytosis patients produce excessive amounts of PGD2, which causes vasodilation, flushing, hypotension, and syncopal episodes. PGD2 is also produced in the brain via an alternative pathway involving a soluble, secreted PGD-synthase also known as beta-trace. In the brain, PGD2 produces normal physiological sleep and lowering of body temperature. Further pharmacological actions include inhibition of platelet aggregation and relaxation of vascular smooth muscle. PGD2 inhibits human ovarian tumor cell proliferation with an IC50 of 6.8 µM. Formal Name: 9alpha,15S-dihydroxy-11-oxo-prosta-5Z,13E-dien-1-oic acid. CAS Number: 41598-07-6. Synonyms: PGD2. Molecular Formula: C20H32O5. Formula Weight: 352.5. Purity: >98%. Formulation: A crystalline solid. Solubility: DMF: >100 mg/ml, DMSO: >50 mg/ml, Ethanol: >75 mg/ml, PBS pH 7.2: >5 mg/ml. SMILES: CCCCCC(O)/C=C/[C@H]1C(=O)CC(O)C1C/C=C\CCCC(=O)O. InChi Code: InChI=1S/C20H32O5/c1-2-3-6-9-15(21)12-13-17-16(18(22)14-19(17)23)10-7-4-5-8-11-20(24)25/h4,7,12-13,15-18,21-22H,2-3,5-6,8-11,14H2,1H3,(H,24,25)/b7-4-,13-12+/t15-,16+,17+,18-/m0/s1. InChi Key: BHMBVRSPMRCCGG-OUTUXVNYSA-N.
Schlagworte: PGD2, 9alpha,15S-dihydroxy-11-oxo-prosta-5Z,13E-dien-1-oic acid
Hersteller: Cayman Chemical
Hersteller-Nr: 12010

Eigenschaften

Anwendung: Bioactive lipid assays
MW: 352.5 D
Formel: C20H32O5
Reinheit: >98%
Format: Crystalline Solid

Datenbank Information

CAS : 41598-07-6| Finde Alternativen

Handhabung & Sicherheit

Lagerung: -20°C
Versand: +20°C (International: -20°C)
Signalwort: Danger
GHS-Piktogramme:
H-Sätze: H302, H360
P-Sätze: P201, P202, P264, P270, P280, P301+310, P308+313, P330, P405, P501
Achtung
Nur für Forschungszwecke und Laboruntersuchungen: Nicht für die Anwendung im oder am Menschen!
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