Prostaglandin D1 Alcohol

Prostaglandin D1 (PGD1) alcohol is the synthetic analog of PGD1 with a primary alcohol in place of the C-1 carboxyl. There are no known reports of its biological activity. PGD1 is the theoretical D-series metabolite of dihomo-gamma-linolenic acid (DGLA), but to date it has not been isolated as a natural product. It is an inhibitor of ADP-induced platelet aggregation in humans with an IC50 value of 320 ng/ml, about 1/10 as potent as PGD2.Formal Name: 1,9alpha,15S-trihydroxy-prost-13E-en-11-one. CAS Number: 1176470-37-3. Synonyms: PGD1 Alcohol. Molecular Formula: C20H36O4. Formula Weight: 340.5. Purity: >99%. Formulation: (Request formulation change), A crystalline solid. Solubility: DMF: 10 mg/ml, DMSO: 10 mg/ml, Ethanol: 15 mg/ml, PBS (7.2): 75 µg/ml when added as a solut. SMILES: CCCCCC(O)/C=C/[C@H]1C(=O)CC(O)C1CCCCCCCO. InChi Code: InChI=1S/C20H36O4/c1-2-3-7-10-16(22)12-13-18-17(19(23)15-20(18)24)11-8-5-4-6-9-14-21/h12-13,16-19,21-23H,2-11,14-15H2,1H3/b13-12+/t16-,17+,18+,19-/m0/s1. InChi Key: SGFHBGFMOSYSBL-KENJKRGESA-N.