Prostaglandin A1

Prostaglandin A1 (PGA1) was first isolated as a dehydration product of the PGE1 compounds found in human semen. It has been shown to cause renal vasodilation, increased urine sodium excretion, and lowered arterial pressure in hypertensive patients. It also has growth-inhibitory activity on tumor cells, the IC50 value for the inhibition of human ovarian cancer is 7.5 µM. Formal Name: 9-oxo-15S-hydroxy-prosta-10,13E-dien-1-oic acid. CAS Number: 14152-28-4. Synonyms: PGA1. Molecular Formula: C20H32O4. Formula Weight: 336.5. Purity: >98%. Formulation: A crystalline solid. Solubility: Acetone: >100 mg/ml, DMF: >75 mg/ml, DMSO: >50 mg/ml, Ethanol: >100 mg/ml, PBS pH 7.2: >2.4 mg/ml. lambdamax: 216 nm. SMILES: CCCCCC(O)/C=C/[C@H]1C=CC(=O)C1CCCCCCC(=O)O. InChi Code: InChI=1S/C20H32O4/c1-2-3-6-9-17(21)14-12-16-13-15-19(22)18(16)10-7-4-5-8-11-20(23)24/h12-18,21H,2-11H2,1H3,(H,23,24)/b14-12+/t16-,17-,18+/m0/s1. InChi Key: BGKHCLZFGPIKKU-LDDQNKHRSA-N.