POV-PC

POV-PC
Artikelnummer Größe Datenblatt Manual SDB Lieferzeit Menge Preis
Cay10031-1 1 mg -

5 - 10 Werktage*

90,00 €
Cay10031-5 5 mg -

5 - 10 Werktage*

405,00 €
Cay10031-10 10 mg -

5 - 10 Werktage*

720,00 €
Cay10031-25 25 mg -

5 - 10 Werktage*

1.575,00 €
 
Oxidized low-density lipoprotien (oxLDL) particles contain low molecular weight species which are... mehr
Produktinformationen "POV-PC"
Oxidized low-density lipoprotien (oxLDL) particles contain low molecular weight species which are cytotoxic and pro-atherogenic. Many of these substances were recently isolated and purified from oxLDL, and identified as phosphatidylcholine species containing a fragmented, oxidized short-chain fatty acid remnant at the sn-2 position. 1-(Palmitoyl)-2-(5-oxovaleroyl)-phosphatidylcholine, or POV-PC, is one of the oxLDL species derived from 2-arachidonoyl or eicosapentanoyl phospholipids. POV-PC confers CD36 scavenger receptor binding affinity more potently than any hydroperoxy PC species, and may be one of the more important structural determinants of oxLDL. Treatment of cultured endothelial cells with POV-PC stimulates monocyte binding, stimulates intracellular cAMP production, and strongly inhibits the LPS-induced binding of neutrophils. Formal Name: 1-palmitoyl-2-(5-oxovaleroyl)-sn-glycero-3-phosphatidylcholine. CAS Number: 121324-31-0. Synonyms: 2-(5-oxovaleryl) Phosphatidylcholine. Molecular Formula: C29H56NO9P. Formula Weight: 593.7. Purity: >98%. Formulation: A solution in ethanol. Solubility: DMF: 15 mg/ml, DMSO: 10 mg/ml, Ethanol: 30 mg/ml, PBS (pH 7.2): 10 mg/ml. SMILES: CCCCCCCCCCCCCCCC(=O)OC[C@H](COP(=O)(O)OCC[N](C)(C)C)OC(=O)CCCC=O. InChi Code: InChI=1S/C29H56NO9P/c1-5-6-7-8-9-10-11-12-13-14-15-16-17-20-28(32)36-25-27(39-29(33)21-18-19-23-31)26-38-40(34,35)37-24-22-30(2,3)4/h23,27H,5-22,24-26H2,1-4H3/t27-/m1/s1. InChi Key: RKIDALSACBQVTN-HHHXNRCGSA-N. Side Chain Carbon Sum: 21:0.
Schlagworte: 2-(5-oxovaleryl) Phosphatidylcholine, 1-palmitoyl-2-(5-oxovaleroyl)-sn-glycero-3-phosphatidylcholine
Hersteller: Cayman Chemical
Hersteller-Nr: 10031

Eigenschaften

Anwendung: Bioactive lipid assays
MW: 593.7 D
Formel: C29H56NO9P
Reinheit: >98%
Format: Solution

Datenbank Information

CAS : 121324-31-0| Finde Alternativen

Handhabung & Sicherheit

Lagerung: -20°C
Versand: +20°C (International: -20°C)
Signalwort: Danger
GHS-Piktogramme:
H-Sätze: H225
P-Sätze: P210, P233, P240, P241, P242, P243, P280, P303+361+353, P370+378, P403+235, P501
Achtung
Nur für Forschungszwecke und Laboruntersuchungen: Nicht für die Anwendung im oder am Menschen!
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