N-Nervonoyl Taurine

N-Nervonoyl Taurine
Artikelnummer Größe Datenblatt Manual SDB Lieferzeit Menge Preis
Cay10007287-1 1 mg -

5 - 10 Werktage*

84,00 €
Cay10007287-5 5 mg -

5 - 10 Werktage*

378,00 €
Cay10007287-10 10 mg -

5 - 10 Werktage*

670,00 €
 
Several different arachidonoyl amino acid conjugates, including N-arachidonoyl dopamine and... mehr
Produktinformationen "N-Nervonoyl Taurine"
Several different arachidonoyl amino acid conjugates, including N-arachidonoyl dopamine and N-arachidonoyl-L-serine, have been isolated and characterized from bovine brain. N-Nervonyl taurine is one of several novel taurine-conjugated fatty acids discovered during mass spectrometry lipidomic analysis of brain and spinal cord from wild-type and fatty acid amide hydrolase (FAAH) knockout mice. The levels of N-nervonyl taurine were elevated ~25 fold in FAAH-/- mice compared to wild-type mice, indicating that FAAH utilizes N-nervonyl taurine as a substrate. However, in vitro experiments with purified FAAH indicate that related N-fatty acyl taurines and ethanolamines of similar chain length are hydrolyzed 2,000-50,000 times more slowly by FAAH compared to oleoyl ethanolamide. The biological function of the taurine fatty acids class of molecules, as well as their relevance to endocannabinoid signaling, remains to be determined. N-acyl taurines bearing polyunsaturated acyl chains can activate members of the transient receptor potential (TRP) family of calcium channels, including TRPV1 and TRPV4. Formal Name: 2-[(1-oxo-15Z-tetracosenyl)amino]-ethanesulfonic acid. Molecular Formula: C26H51NO4S. Formula Weight: 473.8. Purity: >98%. Formulation: A crystalline solid. Solubility: DMF: 5 mg/ml, DMSO: 10 mg/ml, PBS (pH 7.2): 1 mg/ml. SMILES: CCCCCCCC/C=C\CCCCCCCCCCCCCC(=O)NCCS(=O)(=O)O. InChi Code: InChI=1S/C26H51NO4S/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-15-16-17-18-19-20-21-22-23-26(28)27-24-25-32(29,30)31/h9-10H,2-8,11-25H2,1H3,(H,27,28)(H,29,30,31)/b10-9-. InChi Key: QIEYQUYASMRRHE-KTKRTIGZSA-N.
Schlagworte: 2-[(1-oxo-15Z-tetracosenyl)amino]-ethanesulfonic acid
Hersteller: Cayman Chemical
Hersteller-Nr: 10007287

Eigenschaften

Anwendung: Bioactive lipid assays
MW: 473.8 D
Formel: C26H51NO4S
Reinheit: >98%
Format: Crystalline Solid

Datenbank Information

Handhabung & Sicherheit

Lagerung: -20°C
Versand: +20°C (International: -20°C)
Achtung
Nur für Forschungszwecke und Laboruntersuchungen: Nicht für die Anwendung im oder am Menschen!
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