Lumula

Lumula
Artikelnummer Größe Datenblatt Manual SDB Lieferzeit Menge Preis
Cay16685-100 100 µg -

5 - 10 Werktage*

244,00 €
Cay16685-500 500 µg -

5 - 10 Werktage*

732,00 €
Cay16685-1 1 mg -

5 - 10 Werktage*

1.219,00 €
 
Lumula is a hybrid eicosanoid analog that incorporates the docosanoid and prostamide features of... mehr
Produktinformationen "Lumula"
Lumula is a hybrid eicosanoid analog that incorporates the docosanoid and prostamide features of unoprostone (Cay-16680) and bimatoprost (17-phenyl trinor Prostaglandin F2alpha ethyl amide, Cay-16820), respectively, prostaglandin analogs that lack potency at the prostanoid FP receptor. Based on classical structure-activity relationships that have been established for prostanoid receptors, lumula is predicted to have low activity at these receptors. The N-ethyl amide prodrug moiety it inherits from bimatoprost is slow to hydrolyze and the lower side chain modifications inherited from unoprostone interfere with FP receptor binding. Lumula is intended for use as a negative control for testing mechanisms of unoprostone and bimatoprost activity. Formal Name: N-ethyl-9alpha,11alpha-dihydroxy-15-oxo-20a,20b-dihomoprost-5-en-1-amide. Synonyms: Maxeyprost, Unoprostone N-ethyl amide. Molecular Formula: C24H43NO4. Formula Weight: 409.6. Purity: >98%. Formulation: A solution in methyl acetate. Solubility: DMF: 30 mg/ml, DMSO: 25 mg/ml, Ethanol: 50 mg/ml, Ethanol:PBS (pH 7.2): miscible. SMILES: O[C@@H]1[C@H](C/C=C\CCCC(N([H])CC)=O)[C@@H](CCC(CCCCCCC)=O)[C@H](O)C1. InChi Code: InChI=1S/C24H43NO4/c1-3-5-6-7-10-13-19(26)16-17-21-20(22(27)18-23(21)28)14-11-8-9-12-15-24(29)25-4-2/h8,11,20-23,27-28H,3-7,9-10,12-18H2,1-2H3,(H,25,29)/b11-8-/t20-,21-,22+,23-/m1/s1. InChi Key: HKPRCFLRPPLNEN-XKRYCQBQSA-N.
Schlagworte: Maxeyprost, Unoprostone N-ethyl amide, N-ethyl-9alpha,11alpha-dihydroxy-15-oxo-20a,20b-dihomoprost-5-en-1-amide
Hersteller: Cayman Chemical
Hersteller-Nr: 16685

Eigenschaften

Anwendung: Bioactive lipid assays
MW: 409.6 D
Formel: C24H43NO4
Reinheit: >98%
Format: Solution

Datenbank Information

Handhabung & Sicherheit

Lagerung: -20°C
Versand: +20°C (International: -20°C)
Signalwort: Danger
GHS-Piktogramme:
H-Sätze: H225, H319, H336
P-Sätze: P210, P233, P240, P241, P242, P243, P261, P264, P271, P280, P303+361+353, P304+340, P305+351+338, P312, P337+313, P370+378, P403+233, P403+235, P405, P501
Achtung
Nur für Forschungszwecke und Laboruntersuchungen: Nicht für die Anwendung im oder am Menschen!
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