Epibrassinolide

Epibrassinolide is a brassinosteroid that can be isolated from various plants and has been shown to decrease toxicity and stimulate healthy plant growth in plants under stress. Epibrassinolide is also reported to be a potential apoptotic inducer in various cancer cells without affecting the non-tumor cell growth. It has also been shown to protect neuronal PC12 cells from 1-methyl-4-phenylpyridinium-induced oxidative stress and consequent apoptosis in dopaminergic neurons.Formal Name: (1R,3aS,3bS,6aS,8S,9R,10aR,10bS,12aS)-12a-dimethyl-1-[(1S,2R,3R,4R)-2,3-dihydroxy-1,4,5-trimethylhexyl]hexadecahydro-8,9-dihydroxy-10a6H-benz[c]indeno[5,4-e]oxepin-6-one. CAS Number: 78821-43-9. Synonyms: EBL, 24-Epibrassinolide. Molecular Formula: C28H48O6. Formula Weight: 480.7. Purity: >95%. Formulation: (Request formulation change), A crystalline solid. Solubility: DMF: 5 mg/ml, DMF:PBS (pH 7.2) (1:3): 0.25 mg/ml, DMSO: 3 mg/ml, Ethanol: 3 mg/ml. SMILES: O=C1[C@]2([H])[C@@](C[C@@H](O)[C@@H](O)C2)(C)[C@@]3([H])CC[C@@]4(C)[C@](CC[C@]4([H])[C@H](C)[C@@H](O)[C@H](O)[C@H](C)C(C)C)([H])[C@]3([H])CO1. InChi Code: InChI=1S/C28H48O6/c1-14(2)15(3)24(31)25(32)16(4)18-7-8-19-17-13-34-26(33)21-11-22(29)23(30)12-28(21,6)20(17)9-10-27(18,19)5/h14-25,29-32H,7-13H2,1-6H3/t15-,16+,17+,18-,19+,20+,21-,22+,23-,24-,25-,27-,28-/m1/s1. InChi Key: IXVMHGVQKLDRKH-QHBHMFGVSA-N.